大肠杆菌中的一些错配修复活性。
Some mismatch repair activities in Escherichia coli.
作者信息
Radicella J P, Clark E A, Fox M S
机构信息
Department of Biology, Massachusetts Institute of Technology, Cambridge 02139.
出版信息
Proc Natl Acad Sci U S A. 1988 Dec;85(24):9674-8. doi: 10.1073/pnas.85.24.9674.
Abstract
Heterozygous bacteriophage lambda DNA molecules, whose replication requires mismatch correction of a mutant nucleotide in the transcribed strand, provide an assay for localized mismatch repair in Escherichia coli. We describe two systems: one removes the A in C.A or G.A mismatches and the other removes one or the other C in a C.C mismatch. Mutations disabling the first system result in a mutator phenotype that may be identical to mutY.
摘要
杂合噬菌体λDNA分子的复制需要对转录链中的突变核苷酸进行错配校正，这为大肠杆菌中的局部错配修复提供了一种检测方法。我们描述了两种系统：一种去除C.A或G.A错配中的A，另一种去除C.C错配中的一个C。使第一个系统失活的突变会导致一种突变体表型，可能与mutY相同。
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本文引用的文献
1
Localized Negative Interference in Bacteriophage.噬菌体中的局部负干扰
Genetics. 1965 Mar;51(3):369-79. doi: 10.1093/genetics/51.3.369.
2
Effects of DNA heterologies on bacteriophage lambda packaging.DNA异源性对噬菌体λ包装的影响。
Genetics. 1988 Jan;118(1):5-12. doi: 10.1093/genetics/118.1.5.
3
Effects of DNA heterologies on bacteriophage lambda recombination.DNA异源性对噬菌体λ重组的影响。
Genetics. 1988 Jan;118(1):13-9. doi: 10.1093/genetics/118.1.13.
4
Correlation of DNA adenine methylase activity with spontaneous mutability in Escherichia coli K-12.大肠杆菌K-12中DNA腺嘌呤甲基化酶活性与自发突变率的相关性
Gene. 1984 Apr;28(1):123-5. doi: 10.1016/0378-1119(84)90095-7.
5
Methyl-directed repair of DNA base-pair mismatches in vitro.体外甲基化指导的DNA碱基对错配修复
Proc Natl Acad Sci U S A. 1983 Aug;80(15):4639-43. doi: 10.1073/pnas.80.15.4639.
6
Positive selection for loss of tetracycline resistance.对四环素抗性丧失的正向选择。
J Bacteriol. 1980 Aug;143(2):926-33. doi: 10.1128/jb.143.2.926-933.1980.
7
Specific mismatch correction in bacteriophage lambda crosses by very short patch repair.通过极短补丁修复实现噬菌体λ杂交中的特异性错配校正。
Mol Gen Genet. 1983;191(1):118-25. doi: 10.1007/BF00330898.
8
Detection of non-homology-containing heteroduplex molecules.不含同源性的异源双链分子的检测
Nucleic Acids Res. 1983 Jun 25;11(12):3959-71. doi: 10.1093/nar/11.12.3959.
9
Nucleotide sequence of bacteriophage lambda DNA.噬菌体λDNA的核苷酸序列。
J Mol Biol. 1982 Dec 25;162(4):729-73. doi: 10.1016/0022-2836(82)90546-0.
10
New Tn10 derivatives for transposon mutagenesis and for construction of lacZ operon fusions by transposition.用于转座子诱变及通过转座构建lacZ操纵子融合体的新型Tn10衍生物。
Gene. 1984 Dec;32(3):369-79. doi: 10.1016/0378-1119(84)90012-x.
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