Department of General Ophthalmology, Medical University, Lublin, Poland.
Department of Mathematics and Medical Biostatistics, Medical University, Lublin, Poland.
Biomed Res Int. 2018 Mar 18;2018:4954532. doi: 10.1155/2018/4954532. eCollection 2018.
To detect abnormality of the visual function in naïve patients with cystoid diabetic macular edema (DME) using M-charts, Amsler test, and white on white (W/W) and blue on yellow (B/Y) perimetry.
There were 64 eyes included in the study: 30 eyes with DME, 22 eyes with diabetes without DME, and 12 eyes of normal subjects. Conventional W/W perimetry and B/Y perimetry were performed within the central 10° of the visual field. To assess metamorphopsia, Amsler test and M-charts were used.
The rate of detection of metamorphopsia was 37% with Amsler test examination and 50% with M-charts. Specificity of both tests was 100%. We found a significant difference between vertical scores of M-charts in all groups, but not in horizontal scores ( < 0.0001). Mean defect (MD) was 8.9 dB and 3.6 dB and loss variance (LV) 4.8 dB and 3.3 dB ( < 0.0001).
M-chart is more sensitive than Amsler test method for detection of metamorphopsia. The MD and LV are higher in b/y in comparison to W/W perimetry. B/Y perimetry and M-charts are more sensitive than conventional methods for detecting the visual function loss in cystoid DME.
使用 M 图、阿姆斯勒测试以及白对黄(B/Y)和白对白(W/W)视野计检测初诊的囊样糖尿病性黄斑水肿(DME)患者的视觉功能异常。
研究纳入 64 只眼:30 只眼患有 DME,22 只眼患有糖尿病但无 DME,12 只眼为正常对照。在视野中心 10°范围内进行常规 W/W 和 B/Y 视野计检查。为评估变形,使用阿姆斯勒测试和 M 图进行检查。
阿姆斯勒测试检查发现变形的比例为 37%,M 图为 50%。两种测试的特异性均为 100%。我们发现所有组中 M 图的垂直评分均存在显著差异,但水平评分无差异(<0.0001)。平均缺损(MD)为 8.9dB 和 3.6dB,失量方差(LV)为 4.8dB 和 3.3dB(<0.0001)。
M 图比阿姆斯勒测试方法更能检测变形。与 W/W 视野计相比,B/Y 视野计的 MD 和 LV 更高。B/Y 视野计和 M 图比常规方法更能敏感地检测囊样 DME 患者的视觉功能损失。