1 School of Agriculture, Food & Wine, University of Adelaide, Urrbrae, SA, Australia.
2 Healthy Mothers, Babies and Children, South Australian Health and Medical Research Institute, Adelaide, SA, Australia.
J Hum Lact. 2018 Aug;34(3):585-591. doi: 10.1177/0890334418772279. Epub 2018 May 14.
Human milk is a rich source of omega-3 long-chain polyunsaturated fatty acids, which are postulated to be important for brain development. There is a lack of data on the human milk fatty acid composition of Cambodian women compared with data from Western women. Research Aim: The aim of this study was to determine the human milk fatty acid composition of women living in Cambodia and compare it with that of women living in Australia.
Human milk samples from Cambodian ( n = 67) and Australian ( n = 200) mothers were collected at 3 to 4 months postpartum. Fatty acid composition was analyzed using capillary gas chromatography followed by Folch extraction with chloroform/methanol (2:1 v/v), and fat content was measured gravimetrically.
Compared with Australian participants, human milk from Cambodian participants contained a significantly lower level of total fat (2.90 vs. 3.45 g/dL, p = .028), lower percentages of linoleic acid (9.30% vs. 10.66%, p < .0001) and α-linolenic acid (0.42% vs. 0.95%, p < .0001), but higher percentages of arachidonic acid (0.68% vs. 0.38%, p < .0001) and docosahexaenoic acid (0.40% vs. 0.23%, p < .0001).
Differences in human milk fatty acid composition between Cambodian and Australian participants may be explained by differences in the dietary patterns between the two populations.
人乳是 ω-3 长链多不饱和脂肪酸的丰富来源，这些脂肪酸被认为对大脑发育很重要。与西方女性的数据相比，关于柬埔寨女性人乳脂肪酸组成的数据很少。
本研究旨在确定生活在柬埔寨的女性的人乳脂肪酸组成，并将其与生活在澳大利亚的女性进行比较。
在产后 3 至 4 个月收集了来自柬埔寨（n = 67）和澳大利亚（n = 200）母亲的人乳样本。使用毛细管气相色谱法分析脂肪酸组成，然后用氯仿/甲醇（2:1 v/v）进行 Folch 提取，并通过重量法测量脂肪含量。
与澳大利亚参与者相比，柬埔寨参与者的人乳总脂肪含量明显较低（2.90 对 3.45 g/dL，p =.028），亚油酸（9.30%对 10.66%，p <.0001）和α-亚麻酸（0.42%对 0.95%，p <.0001）的百分比较低，但花生四烯酸（0.68%对 0.38%，p <.0001）和二十二碳六烯酸（0.40%对 0.23%，p <.0001）的百分比较高。
柬埔寨和澳大利亚参与者之间人乳脂肪酸组成的差异可能是由于两种人群的饮食模式不同所致。
