20-HETE: Hypertension and Beyond.
作者信息
Roman Richard J, Fan Fan
机构信息
From the Department of Pharmacology, University of Mississippi Medical Center, Jackson.
出版信息
Hypertension. 2018 Jul;72(1):12-18. doi: 10.1161/HYPERTENSIONAHA.118.10269. Epub 2018 May 14.
Abstract
摘要
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本文引用的文献
1
20-HETE promotes glucose-stimulated insulin secretion in an autocrine manner through FFAR1.20-羟基二十碳四烯酸（20-HETE）通过游离脂肪酸受体1（FFAR1）以自分泌方式促进葡萄糖刺激的胰岛素分泌。
Nat Commun. 2018 Jan 12;9(1):177. doi: 10.1038/s41467-017-02539-4.
2
The Blood Pressure-Lowering Effect of 20-HETE Blockade in Mice Is Associated with Natriuresis.20-羟基二十碳四烯酸（20-HETE）阻断对小鼠的降压作用与利钠作用有关。
J Pharmacol Exp Ther. 2017 Dec;363(3):412-418. doi: 10.1124/jpet.117.243618. Epub 2017 Sep 14.
3
Effect of Cytochrome P450 Metabolites of Arachidonic Acid in Nephrology.花生四烯酸的细胞色素P450代谢产物在肾脏病学中的作用
J Am Soc Nephrol. 2017 Oct;28(10):2845-2855. doi: 10.1681/ASN.2017030252. Epub 2017 Jul 12.
4
GPR75 Identified as the First 20-HETE Receptor: A Chemokine Receptor Adopted by a New Family.GPR75被鉴定为首个20-羟基二十碳四烯酸受体：一个被新家族采用的趋化因子受体。
Circ Res. 2017 May 26;120(11):1696-1698. doi: 10.1161/CIRCRESAHA.117.311022.
5
20-HETE Signals Through G-Protein-Coupled Receptor GPR75 (G) to Affect Vascular Function and Trigger Hypertension.20-羟基二十碳四烯酸（20-HETE）通过G蛋白偶联受体GPR75发出信号，影响血管功能并引发高血压。
Circ Res. 2017 May 26;120(11):1776-1788. doi: 10.1161/CIRCRESAHA.116.310525. Epub 2017 Mar 21.
6
Recent developments on the vascular effects of 20-hydroxyeicosatetraenoic acid.20-羟基二十碳四烯酸血管效应的最新进展
Curr Opin Nephrol Hypertens. 2017 Mar;26(2):74-82. doi: 10.1097/MNH.0000000000000302.
7
20-HETE attenuates the response of glucose-stimulated insulin secretion through the AKT/GSK-3β/Glut2 pathway.20-羟基二十碳四烯酸通过AKT/糖原合成酶激酶-3β/葡萄糖转运蛋白2途径减弱葡萄糖刺激的胰岛素分泌反应。
Endocrine. 2016 Nov;54(2):371-382. doi: 10.1007/s12020-016-1031-5. Epub 2016 Aug 27.
8
20-Hydroxyeicosatetraenoic Acid (HETE)-dependent Hypertension in Human Cytochrome P450 (CYP) 4A11 Transgenic Mice: NORMALIZATION OF BLOOD PRESSURE BY SODIUM RESTRICTION, HYDROCHLOROTHIAZIDE, OR BLOCKADE OF THE TYPE 1 ANGIOTENSIN II RECEPTOR.人细胞色素P450（CYP）4A11转基因小鼠中20-羟基二十碳四烯酸（HETE）依赖性高血压：限钠、氢氯噻嗪或阻断1型血管紧张素II受体使血压正常化
J Biol Chem. 2016 Aug 5;291(32):16904-19. doi: 10.1074/jbc.M116.732297. Epub 2016 Jun 13.
9
Molecular mechanisms and cell signaling of 20-hydroxyeicosatetraenoic acid in vascular pathophysiology.20-羟二十碳四烯酸在血管病理生理学中的分子机制和细胞信号转导。
Front Biosci (Landmark Ed). 2016 Jun 1;21(7):1427-63. doi: 10.2741/4465.
10
Cytochrome P450 ω-Hydroxylases in Inflammation and Cancer.细胞色素P450 ω-羟化酶在炎症与癌症中的作用
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