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痤疮丙酸杆菌作为痤疮可能的致病因素及其与痤疮严重程度和类型的关系。 (注:原文中的“spp.”一般指“species”,这里推测是“痤疮丙酸杆菌”相关内容,但原文表述不太完整准确,翻译可能会存在一定局限性)

spp. as a possible aetiopathogenic factor of acne and relation with acne severity and type.

作者信息

Akçınar Ulviye Güvendi, Ünal Emine, Doğruman Al Funda

机构信息

Department of Microbiology, Yildirim Beyazit University, Yenimahalle Training and Research Hospital, Ankara, Turkey.

Department of Parasitology, Faculty of Medicine, Gazi University, Ankara, Turkey.

出版信息

Postepy Dermatol Alergol. 2018 Apr;35(2):174-181. doi: 10.5114/ada.2018.75239. Epub 2018 Apr 24.

Abstract

INTRODUCTION

Acne is a very common skin disease in adolescents and young adults, but it also affects adults. However, its aetiology is not yet fully understood. appears to be associated with multiple skin disorders, but controversy persists. Some reports indicate a connection between acne vulgaris and demodicosis.

AIM

To confirm the association between infestation and acne vulgaris.

MATERIAL AND METHODS

A total of 108 patients were enrolled in the acne group. Acne severity was calculated as GASS and acne type (adolescent and post adolescent) was recorded. An age-sex matched healthy control group comprising 65 individuals were included in the study. Dermatological examinations were performed and an SSSB was used to determine the presence of .

RESULTS

In our study, positivity was seen in 46 (42.6%) patients in the acne group and 8 (12.3%) in the control group; this difference was statistically significant ( < 0.001). A multivariate Backward Step-By-Step Logistic Regression analysis identified the most effective factors for acne development such as positivity ( = 5.565, 95% CI: 2.384-12.99 and < 0.001) and age under 25 years ( = 2.3 and 95% CI: 1.183-4.473 and = 0.014). Alcohol consumption was related to positivity ( = 0.019) in post adolescent acne.

CONCLUSIONS

Our study is the first one to evaluate acne severity, acne type and the relationship to prevalence. We suggest that infestation should be considered when the classical therapies are ineffective especially in cases of post adolescent acne.

摘要

引言

痤疮是青少年和青年成年人中非常常见的一种皮肤病,但也会影响成年人。然而,其病因尚未完全明确。痤疮似乎与多种皮肤疾病有关,但争议仍然存在。一些报告表明寻常痤疮与蠕形螨病之间存在关联。

目的

确认蠕形螨感染与寻常痤疮之间的关联。

材料与方法

痤疮组共纳入108例患者。计算痤疮严重程度(采用全球痤疮分级系统)并记录痤疮类型(青少年型和青春期后型)。研究纳入了由65名个体组成的年龄和性别匹配的健康对照组。进行了皮肤科检查,并使用标准刮拭涂片法确定蠕形螨的存在情况。

结果

在我们的研究中,痤疮组46例(42.6%)患者检测到蠕形螨阳性,对照组8例(12.3%);这种差异具有统计学意义(P<0.001)。多因素逐步向后逻辑回归分析确定了痤疮发生的最有效因素,如蠕形螨阳性(β=5.565,95%可信区间:2.384 - 12.99,P<0.001)和25岁以下年龄(β=2.3,95%可信区间:1.183 - 4.473,P = 0.014)。在青春期后痤疮中,饮酒与蠕形螨阳性有关(β = 0.019)。

结论

我们的研究是首个评估痤疮严重程度、痤疮类型及其与蠕形螨感染率关系的研究。我们建议,当经典疗法无效时,尤其是青春期后痤疮病例,应考虑蠕形螨感染情况。

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