Imperial College London, St Mary's Campus, London, W2 1NY, UK.
Department of Surgery & Cancer, Homerton University Hospital, London, E9 6SR, UK.
Curr Diab Rep. 2019 Aug 30;19(10):90. doi: 10.1007/s11892-019-1217-3.
Obesity is increasing at an alarming rate and now poses a global threat to humankind. In recent years, we have seen the emergence of medical devices to combat the obesity epidemic. These therapeutic strategies are discussed in this review dividing them into gastric and duodenal therapies.
Traditionally, medical devices for obesity such as the intragastric balloon have focused on reducing gastric size, but more recently there has been a shift towards developing devices that modulate neural and hormonal responses to induce early satiety thus reducing oral intake. Medical devices for obesity treatment may have a role in those patients who are struggling to control their weight despite significant lifestyle modifications such as diet and exercise and who decline or are unfit for bariatric surgery. For the wider adoption and integration of these devices in the obesity treatment paradigm, more long-term efficacy and safety data from randomised controlled trials are required.
肥胖率正以惊人的速度增长，目前已对人类健康构成全球性威胁。近年来，我们已经看到了许多对抗肥胖流行的医疗设备的出现。本文将这些治疗策略进行了讨论，将它们分为胃和十二指肠治疗方法。
传统上，用于肥胖治疗的医疗设备（如胃内球囊）主要专注于减小胃的大小，但最近出现了一种趋势，即开发能够调节神经和激素反应以诱导早期饱腹感从而减少口服摄入量的设备。对于那些尽管进行了重大的生活方式改变（如饮食和运动）但仍难以控制体重的患者，或者那些拒绝或不适合进行减重手术的患者，肥胖治疗的医疗设备可能会发挥作用。为了更广泛地采用和整合这些设备用于肥胖治疗，需要更多随机对照试验的长期疗效和安全性数据。
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