大鼠基因组数据库（RGD）入门指南。
A Primer for the Rat Genome Database (RGD).
作者信息
Laulederkind Stanley J F, Hayman G Thomas, Wang Shur-Jen, Smith Jennifer R, Petri Victoria, Hoffman Matthew J, De Pons Jeff, Tutaj Marek A, Ghiasvand Omid, Tutaj Monika, Thota Jyothi, Dwinell Melinda R, Shimoyama Mary
机构信息
Department of Biomedical Engineering, Medical College of Wisconsin and Marquette University, Milwaukee, WI, USA.
Genomic Sciences and Precision Medicine Center, Medical College of Wisconsin, Milwaukee, WI, USA.
出版信息
Methods Mol Biol. 2018;1757:163-209. doi: 10.1007/978-1-4939-7737-6_8.
The laboratory rat, Rattus norvegicus, is an important model of human health and disease, and experimental findings in the rat have relevance to human physiology and disease. The Rat Genome Database (RGD, http://rgd.mcw.edu ) is a model organism database that provides access to a wide variety of curated rat data including disease associations, phenotypes, pathways, molecular functions, biological processes and cellular components for genes, quantitative trait loci, and strains. We present an overview of the database followed by specific examples that can be used to gain experience in employing RGD to explore the wealth of functional data available for the rat.
实验大鼠褐家鼠是人类健康与疾病的重要模型，在大鼠身上的实验结果与人类生理学和疾病相关。大鼠基因组数据库（RGD，http://rgd.mcw.edu ）是一个模式生物数据库，可提供各种经过整理的大鼠数据，包括疾病关联、表型、通路、分子功能、生物学过程以及基因、数量性状位点和品系的细胞成分等信息。我们首先概述该数据库，然后通过具体示例介绍如何利用RGD获取大鼠功能数据，以积累相关经验。
Zotero 插件