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神经调节治疗膀胱过度活动症的新进展?

What Is New in Neuromodulation for Overactive Bladder?

机构信息

Department of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy.

Department of Urology, Ospedale San Giovanni Battista, Turin, Italy.

出版信息

Eur Urol Focus. 2018 Jan;4(1):49-53. doi: 10.1016/j.euf.2018.04.019.

Abstract

UNLABELLED

We reviewed the available studies on efficacy and safety of percutaneous tibial nerve stimulation (PTNS) and sacral nerve modulation (SNM) for overactive bladder (OAB) symptoms not responsive to conservative treatments. We limited our search to randomized trials, in English, with at least 20 adult patients, and 6 mo and 12 wk of follow-up for SNM and PTNS, respectively, published between January 1998 and December 2017. Therapeutic success ranges from 61% to 90% for SNM and from 54% to 79% for PTNS. Both techniques are effective and safe, with no life-threatening adverse effects. PTNS is a less invasive technique that gives good results in short time with fewer side effects.

PATIENT SUMMARY

Sacral nerve modulation and percutaneous tibial nerve stimulation are effective and safe in patients with overactive bladder syndrome not responsive to standard medical therapy.

摘要

目的

我们回顾了经皮胫神经刺激(PTNS)和骶神经调节(SNM)治疗保守治疗无效的膀胱过度活动症(OAB)症状的有效性和安全性的相关研究。我们将研究限定为自 1998 年 1 月至 2017 年 12 月发表的、英文、至少有 20 名成年患者、SNM 和 PTNS 分别随访 6 个月和 12 周的随机试验。SNM 的治疗成功率为 61%至 90%,PTNS 的治疗成功率为 54%至 79%。这两种技术均有效且安全,无危及生命的不良反应。PTNS 是一种侵入性较小的技术,可在短时间内产生良好的效果,且副作用较少。

患者总结

骶神经调节和经皮胫神经刺激对标准药物治疗无效的膀胱过度活动症患者有效且安全。

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