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本文引用的文献

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Epidemiology of Zika Virus Infection. Zika 病毒感染的流行病学。
J Infect Dis. 2017 Dec 16;216(suppl_10):S868-S874. doi: 10.1093/infdis/jix434.
2
Emerging and reemerging arboviruses: A new threat in Eastern Peru.新出现和再次出现的虫媒病毒:秘鲁东部的新威胁。
PLoS One. 2017 Nov 14;12(11):e0187897. doi: 10.1371/journal.pone.0187897. eCollection 2017.
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Consequences of congenital Zika virus infection.先天性 Zika 病毒感染的后果。
Curr Opin Virol. 2017 Dec;27:1-7. doi: 10.1016/j.coviro.2017.09.005. Epub 2017 Nov 6.
4
Update: Interim Guidance for Health Care Providers Caring for Pregnant Women with Possible Zika Virus Exposure - United States (Including U.S. Territories), July 2017.更新:针对照顾可能接触寨卡病毒的孕妇的医疗保健提供者的临时指南 - 美国(包括美国领土),2017年7月
MMWR Morb Mortal Wkly Rep. 2017 Jul 28;66(29):781-793. doi: 10.15585/mmwr.mm6629e1.
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An update on Zika virus infection.寨卡病毒感染的最新进展。
Lancet. 2017 Nov 4;390(10107):2099-2109. doi: 10.1016/S0140-6736(17)31450-2. Epub 2017 Jun 21.
6
Pregnancy Outcomes After Maternal Zika Virus Infection During Pregnancy - U.S. Territories, January 1, 2016-April 25, 2017.2016年1月1日至2017年4月25日美国属地孕期孕妇感染寨卡病毒后的妊娠结局
MMWR Morb Mortal Wkly Rep. 2017 Jun 16;66(23):615-621. doi: 10.15585/mmwr.mm6623e1.
7
Spread of Zika virus in the Americas. Zika 病毒在美洲的传播。
Proc Natl Acad Sci U S A. 2017 May 30;114(22):E4334-E4343. doi: 10.1073/pnas.1620161114. Epub 2017 Apr 25.
8
Echocardiographic findings in infants with presumed congenital Zika syndrome: Retrospective case series study.疑似先天性寨卡综合征婴儿的超声心动图检查结果:回顾性病例系列研究
PLoS One. 2017 Apr 20;12(4):e0175065. doi: 10.1371/journal.pone.0175065. eCollection 2017.
9
Lessons Learned at the Epicenter of Brazil's Congenital Zika Epidemic: Evidence From 87 Confirmed Cases.巴西先天性寨卡疫情震中吸取的教训:87 例确诊病例的证据。
Clin Infect Dis. 2017 May 15;64(10):1302-1308. doi: 10.1093/cid/cix166.
10
Cutaneous Eruption in a U.S. Woman with Locally Acquired Zika Virus Infection.一名美国女性因本地感染寨卡病毒出现皮肤疹
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秘鲁北部无症状孕妇中寨卡病毒感染情况的检测

Detection of Zika virus infection among asymptomatic pregnant women in the North of Peru.

作者信息

Weilg Claudia, Troyes Lucinda, Villegas Zoila, Silva-Caso Wilmer, Mazulis Fernando, Febres Ammy, Troyes Mario, Aguilar-Luis Miguel Angel, Del Valle-Mendoza Juana

机构信息

School of Medicine, Research and Innovation Centre of the Faculty of Health Sciences, Universidad Peruana de Ciencias Aplicadas, Av. San Marcos Cuadra 2, Chorrillos, Lima, Peru.

Laboratorio de Biología Molecular, Instituto de Investigación Nutricional, Lima, Peru.

出版信息

BMC Res Notes. 2018 May 18;11(1):311. doi: 10.1186/s13104-018-3400-z.

DOI:10.1186/s13104-018-3400-z
PMID:29776426
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5960167/
Abstract

OBJECTIVE

To report an outbreak of ZIKV infection among asymptomatic pregnant women during 2016 in the city of Jaen, Cajamarca.

RESULTS

Zika virus RNA was detected in 3.2% (n = 36) of cases by RT-PCR. The mean age of patients positive for ZIKV infection was 29.6 years. 7 patients (19.4%) infected with ZIKV were in their first-trimester of gestation, 13 (36.1%) were in their second-trimester, and 16 (44%) were in their third-trimester. All of the infected pregnant women were asymptomatic. ZIKV infection remains a major public health issue that calls for constant epidemiological surveillance. It can cause the congenital Zika virus syndrome in the newborns of infected mothers. The lack of molecular diagnostic methods in isolated localities and the similarity of symptoms to other arboviral infections, lead to an under-diagnosis of this disease in endemic areas.

摘要

目的

报告2016年在卡哈马卡省哈恩市无症状孕妇中寨卡病毒感染的暴发情况。

结果

通过逆转录聚合酶链反应(RT-PCR)在3.2%(n = 36)的病例中检测到寨卡病毒RNA。寨卡病毒感染阳性患者的平均年龄为29.6岁。7名(19.4%)感染寨卡病毒的孕妇处于妊娠早期,13名(36.1%)处于妊娠中期,16名(44%)处于妊娠晚期。所有感染的孕妇均无症状。寨卡病毒感染仍然是一个重大的公共卫生问题,需要持续进行流行病学监测。它可导致受感染母亲的新生儿患先天性寨卡病毒综合征。偏远地区缺乏分子诊断方法以及症状与其他虫媒病毒感染相似,导致该病在流行地区诊断不足。