Wang Kunjie, Ji Qingjuan, Xu Jialin, Li Hongxia, Zhang Deyi, Liu Xiaoyu, Wu Yujuan, Fan Haiyan
College of Petrochemical Technology, Lanzhou University of Technology, Lanzhou, 730050, China.
Chemistry Department, Nazarbayev University, Astana, Kazakhstan, 010000.
J Fluoresc. 2018 May;28(3):759-765. doi: 10.1007/s10895-018-2237-0. Epub 2018 May 19.
In the present work, we synthesized the carbon quantum dots (CQDs) by one step hydrothermal method using the dried beet powder as the carbon source without additional chemical reagents and functionalization. The as-prepared CQDs are quasi-spherical carbon nanoparticles with diameters of 4-8 nm as well as surface functional groups such as carboxyl and hydroxyl groups, and exhibit good water-solubility, biocompatibility, and strong fluorescence. It is confirmed that amoxicillin (AMO) could enhance the fluorescent intensity of CQDs, the I/I showed a linear correlation between the intensity of fluorescence and the concentration of AMO in a broad range. These superior properties render a potential application of the CQDs in biomedical.
在本工作中，我们以干燥的甜菜粉作为碳源，采用一步水热法合成了碳量子点（CQDs），无需额外的化学试剂和功能化处理。所制备的CQDs为直径4 - 8纳米的准球形碳纳米颗粒，具有羧基和羟基等表面官能团，表现出良好的水溶性、生物相容性和强荧光性。已证实阿莫西林（AMO）可增强CQDs的荧光强度，在较宽范围内荧光强度（I/I）与AMO浓度呈线性相关。这些优异性能使CQDs在生物医学领域具有潜在应用。
