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新型磁控胶囊内镜系统用于胃部检查的体外实验可行性

Feasibility of Novel Magnetically Controlled Cable Capsule Endoscopy System In Vitro Experiments for Gastric Examination.

作者信息

Zhang Yaoping, Qu Lina, Gou Yani, Hao Jinyong, Huang Xiaojun

机构信息

Department of Gastroenterology, Lanzhou University Second Hospital, Lanzhou, Gansu Province, China.

Gansu Provincial Digestive Endoscopy Engineering Research Center, Lanzhou, Gansu Province, China.

出版信息

Gastroenterol Res Pract. 2022 Oct 18;2022:4313647. doi: 10.1155/2022/4313647. eCollection 2022.

Abstract

BACKGROUND

Magnetically controlled capsule endoscopy has been shown to be feasible for the examination of gastric diseases. However, there may be problems, such as low image quality, incomplete esophageal observation, and capsule retention. We developed a novel magnetically controlled cable capsule endoscopy (MCCCE) system and evaluated its feasibility through in vitro experiments.

METHODS

Three experienced endoscopists performed MCCCE on the plastic stomach model and the excised porcine stomach model 5 times, respectively. Outcomes included handle ability, examination time, examination completion, and image quality. The examination completion was accessed by other two blinded endoscopists, and the image quality was compared with conventional gastroscopy (Olympus, GIF-290).

RESULTS

The performance of MCCCE in vitro experiments is excellent, with a mean operation time of 18.5 minutes in the plastic stomach model and 17.3 minutes in the excised porcine stomach model. The visualization rate of the gastric mucosa is >90% in the plastic stomach model and 75-90% in the excised porcine stomach model. The images of MCCCE are very clear, with good color resolution and no image distortion, which seem to be comparable to conventional gastroscopy.

CONCLUSIONS

MCCCE system is feasible for gastric examination in vitro experiments, living animal experiments and human trials need to be further conducted.

摘要

背景

磁控胶囊内镜已被证明可用于胃部疾病检查。然而,可能存在图像质量低、食管观察不完整和胶囊滞留等问题。我们开发了一种新型磁控缆式胶囊内镜(MCCCE)系统,并通过体外实验评估其可行性。

方法

三位经验丰富的内镜医师分别在塑料胃模型和切除的猪胃模型上进行5次MCCCE操作。结果包括操作能力、检查时间、检查完成情况和图像质量。检查完成情况由另外两位不知情的内镜医师评估,图像质量与传统胃镜(奥林巴斯,GIF-290)进行比较。

结果

MCCCE体外实验表现出色,在塑料胃模型中的平均操作时间为18.5分钟,在切除的猪胃模型中为17.3分钟。在塑料胃模型中胃黏膜的可视化率>90%,在切除的猪胃模型中为75-90%。MCCCE的图像非常清晰,具有良好的色彩分辨率且无图像失真,似乎与传统胃镜相当。

结论

MCCCE系统在体外实验中用于胃部检查是可行的,还需要进一步开展活体动物实验和人体试验。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bb5/9596269/b458c1352361/GRP2022-4313647.001.jpg

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