Department of Maxillofacial and Plastic Surgery, Caen University Hospital, 14000, Caen, France; Medecine Faculty of Caen, University of Caen Basse Normandie, 14032, Caen Cedex 5, France.
Department of Maxillofacial and Plastic Surgery, Caen University Hospital, 14000, Caen, France; UNICAEN, EA7451 Equipe BioConnecT, Avenue de la Côte de Nacre, 14000, Caen, France; Medecine Faculty of Caen, University of Caen Basse Normandie, 14032, Caen Cedex 5, France.
J Craniomaxillofac Surg. 2018 Jul;46(7):1059-1064. doi: 10.1016/j.jcms.2018.05.015. Epub 2018 May 21.
Pierre Robin Sequence (PRS) combines mandible microretrognathia, asynchronism of the pharynx and tongue, glossoptosis and, in some cases, cleft palate. Its principal functional consequences are respiratory and feeding problems during the neonatal period. In this study, we focused on the impact of early closure of the cleft at six months on mandibular growth in patients with PRS. We performed a retrospective study of 15 patients followed for PRS and undergoing surgery performed by the same senior surgeon (HB) at our cleft center between 2005 and 2012. These patients underwent early closure of the cleft (at a mean age of 5.87 months) by intravelar veloplasty, as described by Sommerlad. Only one article with exploitable data analyzing facial and mandibular growth in a cephalometric study of children with PRS has been published. The children in this series, constituting the control group for our study, underwent veloplasty between the ages of 12 and 18 months, often accompanied by labioglossoplasty, and the cephalometric study was carried out between the ages of four and seven years. We compared this control group in which surgery was performed at 12-18 months with our series of children undergoing surgery at six months, in a cephalometric study based on teleradiographic profile measurements performed between the ages of four and seven years. We found that early closure of the cleft soft palate yielded results identical to those for the control group in terms of mandibular growth, without the need for labioglossopexy. Finally, early intravelar veloplasty led to early functional improvement in terms of speech and phonation.
Pierre Robin 序列（PRS）结合下颌骨小后缩、咽和舌的不同步、悬雍垂下垂，在某些情况下还伴有腭裂。其主要功能后果是新生儿期的呼吸和喂养问题。在这项研究中，我们关注的是在六个月时早期闭合腭裂对 PRS 患者下颌骨生长的影响。我们对 2005 年至 2012 年期间在我们的腭裂中心由同一位资深外科医生（HB）进行手术的 15 名 PRS 患者进行了回顾性研究。这些患者通过 Sommerlad 描述的内腭裂法进行了早期腭裂闭合（平均年龄为 5.87 个月）。只有一篇文章发表了可用于分析 PRS 儿童头影测量研究中面部和下颌生长的有价值数据。该系列中的儿童构成了我们研究的对照组，他们在 12 至 18 个月之间接受了腭裂手术，通常伴有唇舌成形术，头影测量研究在 4 至 7 岁之间进行。我们将在 12-18 个月进行手术的对照组与我们在 6 个月进行手术的儿童系列进行比较，在 4 至 7 岁之间进行的基于远程射线照相侧位测量的头影测量研究中。我们发现早期闭合软腭裂在促进下颌骨生长方面的结果与对照组相同，而无需进行唇舌固定术。最后，早期的内腭裂法在语音和发音方面实现了早期的功能改善。
