Nuffield Department of Population Health, University of Oxford, Oxford, Oxfordshire, United Kingdom.
The Dartmouth Institute for Health Policy and Clinical Practice, Dartmouth College, Lebanon, New Hampshire, United States of America.
PLoS One. 2018 May 24;13(5):e0197257. doi: 10.1371/journal.pone.0197257. eCollection 2018.
Healthcare interventions, and particularly those in public health may affect multiple diseases and significantly prolong life. No consensus currently exists for how to estimate comparable healthcare costs across multiple diseases for use in health and public health cost-effectiveness models. We aim to describe a method for estimating comparable disease specific English healthcare costs as well as future healthcare costs from diseases unrelated to those modelled.
We use routine national datasets including programme budgeting data and cost curves from NHS England to estimate annual per person costs for diseases included in the PRIMEtime model as well as age and sex specific costs due to unrelated diseases.
The 2013/14 annual cost to NHS England per prevalent case varied between £3,074 for pancreatic cancer and £314 for liver disease. Costs due to unrelated diseases increase with age except for a secondary peak at 30-34 years for women reflecting maternity resource use.
The methodology described allows health and public health economic modellers to estimate comparable English healthcare costs for multiple diseases. This facilitates the direct comparison of different health and public health interventions enabling better decision making.
医疗干预措施，特别是公共卫生干预措施，可能会影响多种疾病，并显著延长寿命。目前对于如何在多个疾病之间估计可比的医疗保健成本，以用于健康和公共卫生成本效益模型，尚无共识。我们旨在描述一种方法，用于估计可比的特定疾病的英语医疗保健成本，以及与模型中所涉及疾病无关的未来医疗保健成本。
我们使用常规的国家数据集，包括来自英格兰国民保健署（NHS England）的项目预算数据和成本曲线，来估计 PRIMEtime 模型中所包含疾病的每人每年成本，以及与无关疾病相关的年龄和性别特定成本。
2013/14 年 NHS England 每例常见病例的年度成本在 £3074（胰腺癌）至 £314（肝病）之间不等。与无关疾病相关的成本随年龄增长而增加，但女性在 30-34 岁时出现了第二个高峰，反映了生育资源的使用。
所描述的方法允许健康和公共卫生经济建模者估计多种疾病的可比英语医疗保健成本。这有助于对不同的健康和公共卫生干预措施进行直接比较，从而做出更好的决策。
