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哈萨克斯坦 Y 染色体单体型参考数据库的建立:对哈萨克人群 27 个 Y-STR 的分析。

Development of the Kazakhstan Y-chromosome haplotype reference database: analysis of 27 Y-STR in Kazakh population.

机构信息

National Laboratory Astana, Nazarbayev University, Astana, Republic of Kazakhstan.

Сentre of Forensic Expertise of the Ministry of Justice of the Republic of Kazakhstan, Astana, Kazakhstan.

出版信息

Int J Legal Med. 2019 Jul;133(4):1029-1032. doi: 10.1007/s00414-018-1859-8. Epub 2018 May 23.

DOI:10.1007/s00414-018-1859-8
PMID:29796706
Abstract

To improve available databases of forensic interest, all Y-STR haplotypes from Kazakh population were presented in this study. The reference database accumulated almost 3650 samples from academic and citizen science. Additionally, 27 Y-STR from Yfiler Plus System were first analyzed in 300 males from Kazakh (Qazaq) populations residing in Kazakhstan. The data is available in the YHDR under accession numbers YA004316 and YA004322. A total of 270 unique haplotypes were observed. Discrimination capacity was 90%. Obtained Y-STR haplotypes exhibited a high intra-population diversity. Analysis of pairwise genetic distances showed lowest R values from Uighur and Mongolian populations.

摘要

为了改善具有法医学意义的现有数据库,本研究呈现了哈萨克人群的所有 Y-STR 单倍型。该参考数据库积累了近 3650 个来自学术和公民科学的样本。此外,在哈萨克斯坦居住的 300 名哈萨克(Qazaq)男性中,首次分析了来自 Yfiler Plus 系统的 27 个 Y-STR。该数据可在 YHDR 中 YA004316 和 YA004322 号访问号下查看。共观察到 270 个独特的单倍型。鉴别能力为 90%。获得的 Y-STR 单倍型表现出较高的群体内多样性。成对遗传距离分析显示,与维吾尔族和蒙古族群体的 R 值最低。

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Revisiting the male genetic landscape of China: a multi-center study of almost 38,000 Y-STR haplotypes.重新审视中国男性的遗传图谱:一项对近38000个Y染色体短串联重复序列(Y-STR)单倍型的多中心研究。
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