Zschäbitz A, Stofft E
Anatomisches Institut, Johannes Gutenberg-Universität Mainz, West Germany.
Histol Histopathol. 1988 Oct;3(4):419-24.
Light-microscopical lectin-binding studies were carried out in healthy and pathologically altered synovial tissue (osteoarthrosis, rheumatoid arthritis (RA)). Seven lectins were studied: Con A, DBA, PNA, RCA, SBA, UEA-I, and WGA. Con A and WGA mark all lining cells and the majority of subintimal synovial cells. RCA and SBA stain only a portion of lining cells, regardless of the basic pathology. The lectin PNA reacts only with RA and arthrotic material, and is thus suitable for the diagnosis of inflammatory changes in synovial tissue. UEA-1 is a consistent marker for capillary endothelium and large vessels.
在健康及病理改变的滑膜组织（骨关节炎、类风湿性关节炎（RA））中进行了光镜凝集素结合研究。研究了七种凝集素：刀豆球蛋白A（Con A）、麦胚凝集素（DBA）、花生凝集素（PNA）、蓖麻凝集素（RCA）、大豆凝集素（SBA）、荆豆凝集素I（UEA-I）和小麦胚凝集素（WGA）。Con A和WGA标记所有衬里细胞和大多数内膜下滑膜细胞。无论基本病理情况如何，RCA和SBA仅对一部分衬里细胞染色。凝集素PNA仅与RA及关节病变材料发生反应，因此适用于诊断滑膜组织中的炎症变化。UEA-1是毛细血管内皮和大血管的一致标记物。
