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耐多药结核性淋巴结炎作为继发性耐多药结核病的初始表现:一例报告

Multidrug-resistant Tuberculosis Lymphadenitis as the Initial Presentation of Secondary Multidrug-resistant Tuberculosis: A Case Report.

作者信息

Ogundipe Temitayo, Otolorin Abiodun, Ogundipe Funmilola, Sran Gopal, Abbas Ghulam, Filani Oladunni

机构信息

Community and Family Medicine, Howard University Hospital.

Pulmonary Medicine, Howard University Hospital.

出版信息

Cureus. 2018 Mar 26;10(3):e2363. doi: 10.7759/cureus.2363.

DOI:10.7759/cureus.2363
PMID:29805932
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5969803/
Abstract

Multidrug-resistant tuberculosis (MDR-TB) occurs when strains of Mycobacterium are resistant to the first-line anti-tuberculosis regimen. We present the case of a 22-year-old immigrant female of African descent who presented to her primary care physician complaining of a two-month history of an enlarging neck mass. Aspiration of the mass, analysis, and culture revealed colonization with a strain of Mycobacterium that was resistant to first-line anti-tuberculosis medications. She was subsequently placed on second line anti-tuberculosis medications.

摘要

当结核分枝杆菌菌株对一线抗结核治疗方案耐药时,就会出现耐多药结核病(MDR-TB)。我们报告了一例22岁的非洲裔移民女性病例,她因颈部肿块增大两个月就诊于初级保健医生。对肿块进行抽吸、分析和培养后发现,其感染了一株对一线抗结核药物耐药的结核分枝杆菌。随后她开始接受二线抗结核药物治疗。

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本文引用的文献

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The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis.耐多药、广泛耐药和不可治愈结核病的流行病学、发病机制、传播、诊断及管理
Lancet Respir Med. 2017 Mar 15. doi: 10.1016/S2213-2600(17)30079-6.
2
Tuberculosis - United States, 2016.美国2016年结核病情况
MMWR Morb Mortal Wkly Rep. 2017 Mar 24;66(11):289-294. doi: 10.15585/mmwr.mm6611a2.
3
Multidrug-Resistant Tuberculous Mediastinal Lymphadenitis, with an Esophagomediastinal Fistula, Mimicking an Esophageal Submucosal Tumor.
The rare multidrug cervical tubercular lymphadenitis in an infant from Iran: A case report and literature review.
来自伊朗的婴儿罕见的多药耐药性宫颈结核性淋巴结炎:病例报告及文献综述
Clin Case Rep. 2020 Dec 4;9(2):681-685. doi: 10.1002/ccr3.3612. eCollection 2021 Feb.
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Scrofula Caused by Multidrug-Resistant Tuberculosis.耐多药结核病所致的瘰疬
Eur J Case Rep Intern Med. 2020 Jan 2;7(1):001390. doi: 10.12890/2020_001390. eCollection 2020.
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Characterization of G-Quadruplex Motifs in espB, espK, and cyp51 Genes of Mycobacterium tuberculosis as Potential Drug Targets.结核分枝杆菌espB、espK和cyp51基因中G-四链体基序作为潜在药物靶点的表征
Mol Ther Nucleic Acids. 2019 Jun 7;16:698-706. doi: 10.1016/j.omtn.2019.04.022. Epub 2019 Apr 30.
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Pol J Radiol. 2018 Dec 29;83:e524-e535. doi: 10.5114/pjr.2018.81408. eCollection 2018.
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