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医学针刺：对成熟肥厚性烧伤瘢痕水分及经表皮水分流失的影响

Medical Needling: Effect on Moisture and Transepidermal Water Loss of Mature Hypertrophic Burn Scars.

作者信息

Busch Kay-Hendrik, Aliu Antigona, Walezko Nicole, Aust Matthias

机构信息

Waldkrankenhaus Bonn, Johanniter Kliniken Bonn.

Medical Faculty, Heinrich-Heine-University.

出版信息

Cureus. 2018 Mar 26;10(3):e2365. doi: 10.7759/cureus.2365.

DOI:10.7759/cureus.2365
PMID:29805934
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5969801/
Abstract

BACKGROUND

Burn scars remain a serious psychological and physiological problem for affected people. Clinical studies and scientific research have already shown that medical needling improves the scar quality in terms of skin elasticity and erythema. At the same time, patients are confronted with a low-risk therapy and face comparatively less postoperative complications.

OBJECTIVE

The goal of our study was to examine the influence of medical needling on the skin moisture and transepidermal water loss (TEWL) of hypertrophic dry scars. Therefore, 20 patients, of an average age of 34.63 years, with deep second- and third-degree burn scars have been treated.

METHODS

Medical needling is performed using a roller covered with needles of 3-mm length. The needling device is rolled over the scar in three directions: vertically, horizontally, and diagonally in order to create as many puncture channels as possible. The puncturing leads to multiple micro-wounds and intradermal bleeding, which evokes the post-needling regeneration cascade. The patients were followed up for 12 months postoperatively. The results have been evaluated by means of objective as well as subjective measurement methods.

RESULTS

The objective measures show that medical needling influences epidermal thickness and improves the epidermal barrier function at a molecular level. Outcomes are marked by a measurable increase in skin moisture and a reduction in TEWL.

CONCLUSION

Medical needling seems to be a promising approach for the treatment of mature hypertrophic burn scars with a focus on skin moisture and TEWL.

摘要

背景

烧伤疤痕对患者来说仍然是一个严重的心理和生理问题。临床研究和科学研究已经表明，医学针刺在改善疤痕皮肤弹性和红斑方面可提升疤痕质量。同时，患者面临的是一种低风险治疗，术后并发症相对较少。

目的

我们研究的目的是检验医学针刺对肥厚性干燥疤痕皮肤水分及经表皮水分流失（TEWL）的影响。因此，我们对20名平均年龄为34.63岁、有深二度和三度烧伤疤痕的患者进行了治疗。

方法

使用覆盖有3毫米长针头的滚轮进行医学针刺。将针刺装置在疤痕上沿三个方向滚动：垂直、水平和对角，以尽可能多地制造穿刺通道。穿刺会导致多处微小伤口和真皮内出血，从而引发针刺后的再生级联反应。术后对患者进行了12个月的随访。结果通过客观和主观测量方法进行评估。

结果

客观测量表明，医学针刺会影响表皮厚度，并在分子水平上改善表皮屏障功能。结果表现为皮肤水分可测量地增加以及TEWL降低。

结论

医学针刺似乎是一种有前景的治疗成熟肥厚性烧伤疤痕的方法，其重点在于皮肤水分和TEWL。

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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e07/5969801/d20d311a3a21/cureus-0010-00000002365-i08.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e07/5969801/8047340ca7d3/cureus-0010-00000002365-i10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e07/5969801/a22c0ad56f8d/cureus-0010-00000002365-i11.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e07/5969801/34614c1c72b2/cureus-0010-00000002365-i12.jpg
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