Juhasz Margit L W, Cohen Joel L
University of California, Department of Dermatology, Irvine, CA, USA.
AboutSkin Dermatology and DermSurgery, Greenwood Village, CO, USA.
Clin Cosmet Investig Dermatol. 2020 Dec 22;13:997-1003. doi: 10.2147/CCID.S267192. eCollection 2020.
Microneedling (MN) is used for the treatment of scars, amongst other indications. Although used in Asia and the Middle East for decades, related to the supposed lack of post-procedure pigmentary alterations even in darker skin types, MN only recently gained attention in the United States as an effective, well-tolerated aesthetic treatment.
A systematic review of the Medline database was completed using search terms "microneedle" or "microneedling" or "micro needle" or "micro needling" and "scar". Included articles were written in English and discussed the use of MN for the treatment of scars in human subjects.
Fifty-eight studies were included for review, with a total of 1845 patients treated for acne scarring, hypertrophic or keloid scars, and those resulting from surgery, trauma, varicella or smallpox. MN and its counterpart fractional radiofrequency MN (FRF-MN) were used as monotherapy or in combination with topical, surgical or systemic modalities. MN and FRF-MN treatment resulted in clinical improvement of scar appearance from baseline. No serious adverse events occurred.
MN is a well-tolerated, minimally invasive procedure that can be used for the treatment of scars with a high level of patient satisfaction. Further clinical studies are needed to develop standardized treatment protocols.
微针疗法(MN)用于治疗瘢痕等多种病症。尽管在亚洲和中东地区已使用数十年,因其即使对于较深肤色类型也被认为术后色素沉着改变较少,但MN直到最近才在美国作为一种有效且耐受性良好的美容治疗方法受到关注。
使用搜索词“微针”或“微针疗法”或“微针”或“微针治疗”以及“瘢痕”对Medline数据库进行了系统综述。纳入的文章为英文撰写,并讨论了MN在人类受试者瘢痕治疗中的应用。
共纳入58项研究进行综述,总计1845例患者接受了痤疮瘢痕、增生性或瘢痕疙瘩性瘢痕以及手术、创伤、水痘或天花所致瘢痕的治疗。MN及其同类分次射频微针疗法(FRF-MN)作为单一疗法或与局部、手术或全身治疗方式联合使用。MN和FRF-MN治疗使瘢痕外观从基线水平得到临床改善。未发生严重不良事件。
MN是一种耐受性良好的微创治疗方法,可用于瘢痕治疗,患者满意度较高。需要进一步开展临床研究以制定标准化治疗方案。