Kaplan M A, Korelitz B I
Department of Psychiatry, Lenox Hill Hospital, New York, NY 10021.
J Clin Gastroenterol. 1988 Jun;10(3):275-8. doi: 10.1097/00004836-198806000-00010.
Thirteen of 43 patients (30%) with inflammatory bowel disease referred for psychiatric consultation were found to be drug dependent, most commonly on oral narcotics. Drug dependence was more frequent in patients with Crohn's disease than ulcerative colitis and many had a borderline personality disorder. The study suggests that drug dependence is not recognized often enough in patients with inflammatory bowel disease and that patients with certain psychiatric disorders are at higher risk of developing it. Recognition of drug dependence is aided by interviewing family members. It is best prevented by seeking and treating the specific cause of pain and by having only one physician assigned to prescribe and manage narcotics.
在因炎症性肠病而接受精神科会诊的43名患者中,有13名(30%)被发现存在药物依赖,最常见的是对口服麻醉药品的依赖。与溃疡性结肠炎患者相比,克罗恩病患者中药物依赖更为常见,且许多患者伴有边缘性人格障碍。该研究表明,炎症性肠病患者中的药物依赖情况常常未得到足够的认识,并且某些精神疾病患者发生药物依赖的风险更高。通过询问家庭成员有助于识别药物依赖。通过寻找并治疗疼痛的具体原因以及仅指定一名医生来开具和管理麻醉药品,可最好地预防药物依赖。