Department of Occupational Medicine and Environmental Health, School of Public Health, Nanjing Medical University, 101 Longmian Avenue, Nanjing, Jiangsu, 211166, People's Republic of China.
Department of Chronic Disease Control and Prevention, Changzhou Center for Disease Control and Prevention, 203 Taishan Road, Changzhou, Jiangsu, 213022, People's Republic of China.
Environ Sci Pollut Res Int. 2018 Aug;25(22):22285-22293. doi: 10.1007/s11356-018-2250-5. Epub 2018 May 28.
Ambient air pollution had been shown strongly associated with cardiovascular diseases. However, the association between air pollution and myocardial infarction (MI) is inconsistent. In the present study, we conducted a time-series study to investigate the association between air pollution and MI. Daily air pollutants, weather data, and MI data were collected from January 2015 to December 2016 in Changzhou, China. Generalized linear model (GLM) was used to assess the immediate effects of air pollutants (PM, PM, NO, SO, and O) on MI. We identified a total of 5545 cases for MI, and a 10-μg/m increment in concentrations of PM and PM was associated with respective increases of 1.636% (95% confidence interval [CI] 0.537-2.740%) and 0.805% (95% CI 0.037-1.574%) for daily MI with 2-day cumulative effects. The associations were more robust among males and in the warm season versus the cold one. No significant effect was found in SO, NO, or O. This study suggested that short-term exposure to PM and PM was associated with the increased MI risks. Our results might be useful for the primary prevention of MI exacerbated by air pollutants.
大气污染已被证实与心血管疾病密切相关。然而，空气污染与心肌梗死（MI）之间的关联并不一致。在本研究中，我们进行了一项时间序列研究，以调查空气污染与 MI 之间的关系。我们收集了 2015 年 1 月至 2016 年 12 月中国常州的每日空气污染物、气象数据和 MI 数据。广义线性模型（GLM）用于评估空气污染物（PM、PM、NO、SO 和 O）对 MI 的即时影响。我们确定了总共 5545 例 MI 病例，与浓度升高 10μg/m 相比，PM 和 PM 的浓度分别增加了 1.636%（95%置信区间[CI]0.537-2.740%）和 0.805%（95%CI0.037-1.574%），每日 MI 有 2 天的累积效应。在男性和温暖季节中，这种关联更为明显，而在寒冷季节中则不明显。SO、NO 或 O 没有显著影响。这项研究表明，短期暴露于 PM 和 PM 与 MI 风险增加有关。我们的研究结果可能对因空气污染物而加剧的 MI 的初级预防有用。
