酵母中染色体长度的遗传控制。

Walmsley R M, Petes T D

Proc Natl Acad Sci U S A. 1985 Jan;82(2):506-10. doi: 10.1073/pnas.82.2.506.

The chromosomes of the yeast Saccharomyces cerevisiae terminate with sequences that have the form poly(C1-3-A). In this paper, we show that within an individual yeast strain all chromosomes end with tracts of poly(C1-3-A) of similar lengths; however, different strains can have tracts that vary in length by a factor of two. By a genetic analysis, we demonstrate that yeast cells have a mechanism that allows them to change rapidly the length of their chromosomes by altering the length of the poly(C1-3-A) tract.

酿酒酵母的染色体末端具有多聚（C1-3-A）形式的序列。在本文中，我们表明在单个酵母菌株内，所有染色体末端的多聚（C1-3-A）片段长度相似；然而，不同菌株的片段长度可能相差两倍。通过遗传分析，我们证明酵母细胞有一种机制，使其能够通过改变多聚（C1-3-A）片段的长度来快速改变染色体的长度。