Blumenfeld W, Egbert B M, Sagebiel R W
Arch Pathol Lab Med. 1985 Feb;109(2):123-7.
The biopsies of all lesions clinically thought to be suspicious for Kaposi's sarcoma (KS) were reviewed over a 15-month period. A diagnosis of KS was made in 40 of 106 biopsies (38%). The cases in which a diagnosis other than KS was made included dermatofibroma, hemangioma, and scar. This second group comprised 59 of 106 cases (56%). A third group included some lesions that had an atypical vascular proliferation, but in which the changes were insufficient for a definite diagnosis of KS. The presence of abnormally shaped vessels, especially those classified as irregular, was the best single criterion to diagnose KS in its early stages. In later stages, the neoplasm assumes a nodular configuration with typical, slitlike vascular channels. At the periphery of such nodules dilated, irregularly shaped vessels similar to those of the early lesions are often seen. The histologic features which help in the diagnosis of KS from other histologic entities are reviewed.
在15个月的时间里，对所有临床上认为可疑为卡波西肉瘤（KS）的病变活检标本进行了回顾。106例活检标本中有40例（38%）诊断为KS。诊断为非KS的病例包括皮肤纤维瘤、血管瘤和瘢痕。这第二组包括106例中的59例（56%）。第三组包括一些具有非典型血管增生但变化不足以明确诊断为KS的病变。异常形状的血管，尤其是那些被归类为不规则的血管，是早期诊断KS的最佳单一标准。在后期，肿瘤呈现结节状结构，伴有典型的裂隙状血管通道。在这些结节的周边，常常可以看到与早期病变相似的扩张、形状不规则的血管。本文回顾了有助于从其他组织学实体中诊断KS的组织学特征。
