Kazantseva I A, Kalamkarian A A, Kerimov S G, Karelina T V
Arkh Patol. 1985;47(11):75-80.
Chaotic angiogenesis and permanent presence of spindle cells with a variable degree of nuclear atypia in the nodular aid tumourous foci represent important diagnostic criteria of Kaposi's sarcoma (KS). At early stages or, on the contrary, in the persistent lesions morphological picture is not sufficiently characteristic and the diagnosis cannot be established on the basis of histological examination only; evaluation of the clinical and morphological data and repeated biopsy are necessary in such cases. The degree of manifestation of a spindle-cell component and the degree of its anaplasia are not determining factors in the prognosis of disease.
在结节状辅助性肿瘤病灶中,血管生成紊乱以及梭形细胞持续存在且伴有不同程度的核异型性,是卡波西肉瘤(KS)的重要诊断标准。在疾病早期,或者相反,在持续性病变中,形态学表现并不具有足够的特征性,仅靠组织学检查无法确诊;在这种情况下,需要评估临床和形态学数据并进行重复活检。梭形细胞成分的表现程度及其间变程度并非疾病预后的决定性因素。