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新生儿和婴儿的细菌性脑膜炎——超声图像

Bacterial meningitis in neonates and infants - the sonographic picture.

作者信息

Littwin Błażej, Pomiećko Andrzej, Stępień-Roman Monika, Spârchez Zeno, Kosiak Wojciech

机构信息

Department of Neonatology, Polanki Children's Hospital in Gdańsk, Gdańsk, Poland.

Laboratory of Diagnostic Ultrasound and Biopsy, Department of Pediatrics, Oncology, Hematology and Endocrinology, University Clinical Center in Gdańsk, Gdańsk, Poland.

出版信息

J Ultrason. 2018 Mar;18(72):63-70. doi: 10.15557/JoU.2018.0010. Epub 2018 Mar 30.

Abstract

Bacterial meningitis is a major diagnostic and therapeutic problem among children and neonates, with severe, rapidly progressing course and potentially life-threatening complications. Early antibacterial treatment is essential for the patient's favorable prognosis. Cerebral imaging plays an important role in the diagnostic process alongside physical examination and laboratory tests. Magnetic resonance imaging is the gold standard for diagnosing bacterial meningitis. Because of limited availability of magnetic resonance imaging, cranial ultrasound is the first imaging procedure to be performed (if the anterior fontanelle is preserved providing an adequate acoustic window). The safety and reliability of ultrasound examination, possibility to perform the examination at bedside without the need for sedation make cranial ultrasound a useful tool both for preliminary diagnostic investigation and for the monitoring of both treatment and long-term complications. Sonographic findings in patients with bacterial meningitis and possible complications are diverse. Changes can be seen on the surface of the brain, in the extra-axial space, in the ventricular system and in brain tissue. In some cases they can also be visible in the lumbosacral segment of the spinal cord. This paper presents ultrasound characteristics of lesions associated with bacterial meningitis in neonates and infants, based on the authors' own material and data from the available literature.

摘要

细菌性脑膜炎是儿童和新生儿面临的一个重大诊断和治疗难题,其病程严重且进展迅速,可能引发危及生命的并发症。早期抗菌治疗对患者的良好预后至关重要。在诊断过程中,脑部成像与体格检查和实验室检查同样重要。磁共振成像(MRI)是诊断细菌性脑膜炎的金标准。由于MRI设备有限,头颅超声是首先进行的成像检查(前提是前囟未闭,能提供足够的声窗)。超声检查的安全性和可靠性,以及无需镇静即可在床边进行检查的可能性,使头颅超声成为初步诊断调查以及治疗和长期并发症监测的有用工具。细菌性脑膜炎患者及其可能并发症的超声表现多种多样。可在脑表面、轴外间隙、脑室系统及脑组织中见到变化。在某些情况下,脊髓腰骶段也可见到这些变化。本文基于作者自身材料及现有文献数据,介绍了新生儿和婴儿细菌性脑膜炎相关病变的超声特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cea6/5911721/b8074646c0d5/JoU-2018-0010-g001.jpg

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