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接受透析治疗的儿童和青少年口腔检查结果与实验室检查之间的关联:一项横断面研究。

Association between oral findings and laboratory tests in children and adolescents undergoing dialysis: A cross- sectional study.

作者信息

Esmaeeli Aida, Esmaeeli Mohamad, Ebrahimi Masoumeh, Nasehi Atefeh

机构信息

Dentist,Private Practice, Mashhad, Iran.

Associate Professor of Pediatric Nephrology,Mashhad University of Medical Sciences, Mashhad, Iran.

出版信息

J Clin Exp Dent. 2018 May 1;10(5):e462-e468. doi: 10.4317/jced.54470. eCollection 2018 May.

DOI:10.4317/jced.54470
PMID:29849971
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5971078/
Abstract

BACKGROUND

Diagnosis of oral complications in the dialysis patients is important to prevent potential infections. The aim of this cross-sectional study was to compare oral findings in dialysis patients with healthy individuals and determination of the correlation of these findings and laboratory tests.

MATERIAL AND METHODS

In this cross-sectional study, DMFT, dmft, DI , CI , OHIS , PI, GI and enamel defects were evaluated in 25 hemodialysis patients, 30 peritoneal dialysis patients and 26 healthy individuals. Then the correlation of laboratory tests (including Hemoglobin, Urea, Creatinine, Ca, Na, Ph, K and ALP) and oral findings was determined in each groups using SPSS (Version 16). Data analyzed with One-way ANOVA test, Chi-Square , Kruskal-Wallis , Tukey's test and Fisher's-Exact test.

RESULTS

Findings revealed significant differences in dmft, DI, CI, OHIs, PI and GI between study groups. A positive correlation between Ca and DI was found in hemodialysis group. In peritoneal dialysis group positive significant correlations between DMFT index and Urea, Cr , ALP and K , between OHIs and K , between PI and Cr and negative correlations between Na and CI and OHIs were found.

CONCLUSIONS

Presence of oral problems in dialysis patients, especially hemodialysis, indicate the necessity of appropriate therapeutic considerations in these patients. The correlation of blood biochemical compounds and oral status in dialysis patients may warn clinicians to control the level of the biochemical blood compounds for oral health improvement. Hemodialysis, laboratory tests, oral findings, peritoneal dialysis.

摘要

背景

诊断透析患者的口腔并发症对于预防潜在感染很重要。这项横断面研究的目的是比较透析患者与健康个体的口腔检查结果,并确定这些结果与实验室检查之间的相关性。

材料与方法

在这项横断面研究中,对25名血液透析患者、30名腹膜透析患者和26名健康个体的恒牙龋失补牙数(DMFT)、乳牙龋失补牙数(dmft)、龋病指数(DI)、牙结石指数(CI)、口腔卫生指数(OHIS)、菌斑指数(PI)、牙龈指数(GI)和牙釉质缺陷进行了评估。然后使用SPSS(版本16)确定每组实验室检查(包括血红蛋白、尿素、肌酐、钙、钠、磷、钾和碱性磷酸酶)与口腔检查结果之间的相关性。数据采用单因素方差分析、卡方检验、Kruskal-Wallis检验、Tukey检验和Fisher精确检验进行分析。

结果

研究结果显示,各研究组之间在dmft、DI、CI、OHIs、PI和GI方面存在显著差异。血液透析组中钙与DI呈正相关。在腹膜透析组中,发现DMFT指数与尿素、肌酐、碱性磷酸酶和钾呈显著正相关,OHIs与钾呈正相关,PI与肌酐呈正相关,钠与CI和OHIs呈负相关。

结论

透析患者,尤其是血液透析患者存在口腔问题,表明对这些患者进行适当治疗考虑的必要性。透析患者血液生化成分与口腔状况的相关性可能会提醒临床医生控制血液生化成分水平以改善口腔健康。血液透析、实验室检查、口腔检查结果、腹膜透析。

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Oral health status in Iranian hemodialysis patients.伊朗血液透析患者的口腔健康状况。
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Oral health and inflammation in patients with end-stage renal failure.终末期肾衰竭患者的口腔健康与炎症
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