Caprez Jennifer, Rahim Umar, Ansari Amna, Lodhi Muhammad Uzair, Rahim Mustafa
Department of Medicine, Appalachian Regional Healthcare, Beckley, Lincoln Memorial University-Debusk College of Osteopathic Medicine.
Pre-Medical Student, Department of Sciences, Queens University of Charlotte, Nc.
Cureus. 2018 Mar 30;10(3):e2397. doi: 10.7759/cureus.2397.
Capecitabine has several side effects, most common of which is Hand-Foot syndrome (HFS); however, less frequently reported is capecitabine-associated hyperpigmentation. The hyperpigmentation associated with this drug has been documented to involve the hands and feet and, less commonly, the mucous membranes of the mouth. To our knowledge, it has never been documented to involve the face. We report a case of a patient with capecitabine-induced Hand-Foot Syndrome (HFS), who also presented with hyperpigmentation of the hands, feet, oral mucosa, and face.
卡培他滨有多种副作用，其中最常见的是手足综合征（HFS）；然而，卡培他滨相关的色素沉着报道较少。与这种药物相关的色素沉着已被记录涉及手和脚，较少见的是口腔黏膜。据我们所知，从未有过涉及面部的记录。我们报告一例患有卡培他滨诱导的手足综合征（HFS）的患者，该患者还出现了手、脚、口腔黏膜和面部的色素沉着。
