Brophy Carl M, Hoh Daniel J
J Neurosurg Spine. 2018 Aug;29(2):130-134. doi: 10.3171/2018.1.SPINE17867. Epub 2018 Jun 1.
Cervical disc arthroplasty (CDA) has received widespread attention as an alternative to anterior fusion due to its similar neurological and functional improvement, with the advantage of preservation of segmental motion. As CDA becomes more widely implemented, the potential for unexpected device-related adverse events may be identified. The authors report on a 48-year-old man who presented with progressive neurological deficits 3 years after 2-level CDA was performed. Imaging demonstrated periprosthetic osteolysis of the vertebral endplates at the CDA levels, with a heterogeneously enhancing ventral epidural mass compressing the spinal cord. Diagnostic workup for infectious and neoplastic processes was negative. The presumptive diagnosis was an inflammatory pannus formation secondary to abnormal motion at the CDA levels. Posterior cervical decompression and instrumented fusion was performed without removal of the arthroplasty devices or the ventral epidural mass. Postoperative imaging at 2 months demonstrated complete resolution of the compressive pannus, with associated improvement in clinical symptoms. Follow-up MRI at > 6 months showed no recurrence of the pannus. At 1 year postoperatively, CT scanning revealed improvement in periprosthetic osteolysis. Inflammatory pannus formation may be an unexpected complication of abnormal segmental motion after CDA. This rare etiology of an epidural mass associated with an arthroplasty device should be considered, in addition to workup for other potential infectious or neoplastic mass lesions. In symptomatic individuals, compressive pannus lesions can be effectively treated with fusion across the involved segment without removal of the device.
颈椎间盘置换术(CDA)作为前路融合术的替代方法,因其在神经功能改善方面效果相似且具有保留节段活动度的优势而受到广泛关注。随着CDA的应用越来越广泛,可能会发现一些意想不到的与器械相关的不良事件。作者报告了一名48岁男性,在接受双节段CDA手术后3年出现进行性神经功能缺损。影像学检查显示CDA节段椎体终板假体周围骨质溶解,腹侧硬膜外肿块不均匀强化并压迫脊髓。针对感染和肿瘤性病变的诊断性检查结果为阴性。推测诊断为CDA节段异常活动继发的炎性血管翳形成。行后路颈椎减压及器械辅助融合术,未取出置换器械或腹侧硬膜外肿块。术后2个月的影像学检查显示压迫性血管翳完全消退,临床症状相应改善。术后6个月以上的随访MRI显示血管翳未复发。术后1年,CT扫描显示假体周围骨质溶解有所改善。炎性血管翳形成可能是CDA术后节段异常活动的一种意想不到的并发症。除了对其他潜在的感染性或肿瘤性肿块病变进行检查外,还应考虑这种与置换器械相关的硬膜外肿块的罕见病因。对于有症状的患者,通过跨越受累节段进行融合可有效治疗压迫性血管翳病变,而无需取出器械。