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危重症老年患者(≥90 岁):临床特征、转归和经济影响。

Critically ill elderly patients (≥ 90 years): Clinical characteristics, outcome and financial implications.

机构信息

Emergency Department, Hautepierre Hospital, University Hospital of Strasbourg, Strasbourg, France.

INSERM (French National Institute of Health and Medical Research), UMR 1260, Regenerative NanoMedicine (RNM), Fédération de Médecine Translationnelle (FMTS), University of Strasbourg, Strasbourg, France.

出版信息

PLoS One. 2018 Jun 1;13(6):e0198360. doi: 10.1371/journal.pone.0198360. eCollection 2018.

Abstract

BACKGROUND

Patients aged over 90 are being admitted to intensive care units (ICUs) with increasing frequency. The appropriateness of such decisions still remains controversial due to questionable outcome, limited resources and costs. Our objective was to determine the clinical characteristics and outcome in elderly patients (≥ 90 years) admitted in a medical ICU, with an additional focus on medico-economic implications.

METHODS

We reviewed the charts of all patients (≥ 90 years) admitted to our ICU. We compared them with all other ICU patients (< 90 years), sought to identify ICU mortality predictors and also performed a long-term survival follow-up.

RESULTS

In the study group of 317 stays: median age was 92 years (IQR: 91-94 years); most patients were female (71.3%.). Acute respiratory failure (52.4%) was the main admission diagnosis; mean SAPS II was 55.6±21.3; half the stays (49.2%) required mechanical ventilation (duration: 7.2±8.8 days); withholding and withdrawing decisions were made for 33.4% of all stays. ICU and hospital mortality rates were 35.7% and 42.6% respectively. Mechanical ventilation (OR = 4.83, CI95%: 1.59-15.82) was an independent predictor of ICU mortality whereas age was not (OR = 0.88, CI95%: 0.72-1.08). Social security reimbursement was significantly lower in the study group compared with all other ICU stays, both per stay (13,160 vs 22,092 Euros, p< 0.01) and per day of stay (p = 0.03).

CONCLUSION

Among critically ill elderly patients (≥ 90 years), chronological age was not an independent factor of ICU mortality. ICU care-related costs in this population should not be considered as a limiting factor for ICU admission.

摘要

背景

年龄在 90 岁以上的患者被送入重症监护病房(ICU)的频率越来越高。由于结果不确定、资源有限和成本高,此类决策的适当性仍存在争议。我们的目的是确定入住内科 ICU 的老年患者(≥90 岁)的临床特征和转归,并特别关注医疗经济方面的影响。

方法

我们回顾了所有入住我们 ICU 的患者(≥90 岁)的病历。我们将他们与所有其他 ICU 患者(<90 岁)进行了比较,试图确定 ICU 死亡率的预测因素,并进行了长期生存随访。

结果

在研究组的 317 例入住中:中位年龄为 92 岁(IQR:91-94 岁);大多数患者为女性(71.3%)。急性呼吸衰竭(52.4%)是主要的入院诊断;平均 SAPS II 为 55.6±21.3;一半的入住(49.2%)需要机械通气(持续时间:7.2±8.8 天);33.4%的所有入住都做出了放弃和撤回的决定。ICU 和医院死亡率分别为 35.7%和 42.6%。机械通气(OR=4.83,95%CI:1.59-15.82)是 ICU 死亡率的独立预测因素,而年龄不是(OR=0.88,95%CI:0.72-1.08)。与所有其他 ICU 入住相比,研究组的社会保障报销明显较低,无论是每次入住(13160 欧元与 22092 欧元,p<0.01)还是每天入住(p=0.03)。

结论

在危重老年患者(≥90 岁)中,年龄并不是 ICU 死亡率的独立因素。在这一人群中,与 ICU 护理相关的费用不应被视为 ICU 入住的限制因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9da/5983531/cf13e4d304b0/pone.0198360.g001.jpg

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