Department of Biomedical Engineering, University of Connecticut, Storrs, CT 06269 USA.
College of Nursing, University of Massachusetts Amherst, Amherst, MA 01003, USA.
Sensors (Basel). 2018 May 26;18(6):1719. doi: 10.3390/s18061719.
The detection of intrathoracic volume retention could be crucial to the early detection of decompensated heart failure (HF). Transthoracic Bioimpedance (TBI) measurement is an indirect, promising approach to assessing intrathoracic fluid volume. Gel-based adhesive electrodes can produce skin irritation, as the patient needs to place them daily in the same spots. Textile electrodes can reduce skin irritation; however, they inconveniently require wetting before each use and provide poor adherence to the skin. Previously, we developed waterproof reusable dry carbon black polydimethylsiloxane (CB/PDMS) electrodes that exhibited a good response to motion artifacts. We examined whether these CB/PDMS electrodes were suitable sensing components to be embedded into a monitoring vest for measuring TBI and the electrocardiogram (ECG). We recruited = 20 subjects to collect TBI and ECG data. The TBI parameters were different between the various types of electrodes. Inter-subject variability for copper-mesh CB/PDMS electrodes and Ag/AgCl electrodes was lower compared to textile electrodes, and the intra-subject variability was similar between the copper-mesh CB/PDMS and Ag/AgCl. We concluded that the copper mesh CB/PDMS (CM/CB/PDMS) electrodes are a suitable alternative for textile electrodes for TBI measurements, but with the benefit of better skin adherence and without the requirement of wetting the electrodes, which can often be forgotten by the stressed HF subjects.
检测胸腔内容量潴留对于早期发现失代偿性心力衰竭(HF)可能至关重要。经胸生物阻抗(TBI)测量是一种评估胸腔内液体量的间接且有前景的方法。基于凝胶的粘性电极会产生皮肤刺激,因为患者需要每天将它们放置在相同部位。纺织电极可以减少皮肤刺激;然而,它们在每次使用前需要不方便地进行湿润处理,并且对皮肤的粘附性较差。此前,我们开发了防水可重复使用的干炭黑聚二甲基硅氧烷(CB/PDMS)电极,其对运动伪影表现出良好的响应。我们研究了这些CB/PDMS电极是否是适合嵌入监测背心以测量TBI和心电图(ECG)的传感组件。我们招募了20名受试者来收集TBI和ECG数据。不同类型电极之间的TBI参数有所不同。与纺织电极相比,铜网CB/PDMS电极和Ag/AgCl电极的受试者间变异性较低,并且铜网CB/PDMS电极和Ag/AgCl电极的受试者内变异性相似。我们得出结论,铜网CB/PDMS(CM/CB/PDMS)电极是用于TBI测量的纺织电极的合适替代品,但具有更好的皮肤粘附性且无需湿润电极的优点,而这一点经常会被处于压力下的HF患者遗忘。