Bhardwaj Ashutosh, Srivastava Nikhil, Rana Vivek, Adlakha Vivek Kumar, Asthana Ashish Kumar
Department of Paedodontics and Preventive Dentistry, Subharti Dental College, Meerut, Uttar Pradesh, India.
Department of Microbiology, Subharti Medical College, Meerut, Uttar Pradesh, India.
Ayu. 2017 Jan-Jun;38(1-2):70-75. doi: 10.4103/ayu.AYU_72_16.
In endodontics, despite careful instrumentation and antimicrobial irrigation, root canals still harbor cultivable microorganisms. Such cases require intra canal medicament that eliminates the microbial inhabitants from the canals. Recent trend advocates the use of herbal extracts due to easy availability, cost-effectiveness, low toxicity, and lack of microbial resistance. Hence, in the present study, , , and extracts were used as intracanal medicaments.
This study aimed to evaluate and compare the antibacterial efficacy of , , extracts, and chlorhexidine against , when used as intracanal medicaments.
One hundred and twenty-five extracted human teeth, inoculated with , were divided into four experimental groups and a control group ( = 25 in each group). The experimental groups were treated with chlorhexidine, , , and extracts and their antibacterial property was evaluated by estimating microbial counting (CFU/ml).
The reduction in bacterial count for chlorhexidine, , , and groups was 60.76%, 51.98%, 37.73%, and 34.93%, respectively. Statistically significant difference in reduction of bacterial count was observed in all the groups, when compared with the control group.
Among all the herbal extracts, was found to be the most potent medicament followed by and . However, chlorhexidine was found to be at epic.
在牙髓病学中,尽管进行了仔细的根管预备和抗菌冲洗,根管内仍存在可培养的微生物。此类病例需要使用根管内药物来清除根管内的微生物。由于易于获取、成本效益高、毒性低且不存在微生物耐药性,最近的趋势提倡使用草药提取物。因此,在本研究中,[此处原文缺失三种草药名称]提取物被用作根管内药物。
本研究旨在评估和比较[此处原文缺失三种草药名称]提取物和氯己定作为根管内药物时对[此处原文缺失一种细菌名称]的抗菌效果。
125颗接种了[此处原文缺失一种细菌名称]的拔除人类牙齿被分为四个实验组和一个对照组(每组n = 25)。实验组分别用氯己定、[此处原文缺失三种草药名称]提取物处理,并通过估计微生物计数(CFU/ml)来评估其抗菌性能。
氯己定、[此处原文缺失三种草药名称]组的细菌计数减少率分别为60.76%、51.98%、37.73%和34.93%。与对照组相比,所有组的细菌计数减少均有统计学显著差异。
在所有草药提取物中,[此处原文缺失一种草药名称]被发现是最有效的药物,其次是[此处原文缺失两种草药名称]。然而,氯己定被发现是最有效的。