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高度近视患者视盘及视乳头周围组织光学相干断层扫描的变化

Optic disc and peripapillary changes by optic coherence tomography in high myopia.

作者信息

Pan Ting, Su Yun, Yuan Song-Tao, Lu Hang-Cheng, Hu Zi-Zhong, Liu Qing-Huai

机构信息

Department of Ophthalmology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu Province, China.

出版信息

Int J Ophthalmol. 2018 May 18;11(5):874-880. doi: 10.18240/ijo.2018.05.25. eCollection 2018.

DOI:10.18240/ijo.2018.05.25
PMID:29862190
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5957043/
Abstract

Myopia, a worldwide condition, is a multifactorial disease resulting in many ocular complications. Early onset of myopia has a great tendency to develop high myopia and pathological myopia later in life. The pathophysiology and progression of myopia is still unclear. Owing to its involving in visual function, optic disc and peripapillary change in high myopia can't be neglected, and it may help in better understanding of the pathophysiology or mechanism of myopia progression. Recently, advanced imaging techniques have been developed, such as optical coherence tomography (OCT), allowing for better detecting of optic disc and peripapillary change. OCT is a high-resolution and noninvasive measurement for detection of ocular structure. Herein, we provide an updated review of optic disc and peripapillary change in OCT image, including its characteristics and clinical significance. We also propose some problems needed further investigation.

摘要

近视是一种全球性的病症,是一种多因素疾病,会导致许多眼部并发症。近视的早发极有可能在以后的生活中发展为高度近视和病理性近视。近视的病理生理学和进展仍不清楚。由于其涉及视觉功能,高度近视中的视盘和视乳头周围变化不容忽视,这可能有助于更好地理解近视进展的病理生理学或机制。最近,已经开发出了先进的成像技术,如光学相干断层扫描(OCT),能够更好地检测视盘和视乳头周围变化。OCT是一种用于检测眼部结构的高分辨率无创测量方法。在此,我们对OCT图像中的视盘和视乳头周围变化进行了更新综述,包括其特征和临床意义。我们还提出了一些需要进一步研究的问题。

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本文引用的文献

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Horizontal and vertical optic disc rotation. The Beijing Eye Study.水平和垂直视盘旋转。北京眼病研究。
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Ganglion cell-inner plexiform layer and retinal nerve fiber layer thickness according to myopia and optic disc area: a quantitative and three-dimensional analysis.根据近视和视盘面积分析神经节细胞-内网状层及视网膜神经纤维层厚度:定量与三维分析
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