1st Department of Obstetrics and Gynecology, Athens Medical School , Alexandra General Hospital, 9 Aristeidou Street , 17563 P. Faliro, Athens, Greece.
3rd Department of Obstetrics and Gynecology, Athens Medical School, Attikon General Hospital, Athens, Greece.
BMC Pregnancy Childbirth. 2018 Jun 4;18(1):206. doi: 10.1186/s12884-018-1848-4.
Delayed interval intertwin delivery rates are expected to rise during the next years as potent and targeted tocolytic agents are employed and antenatal surveillance methods become more sophisticated and specific in predicting the critical delivery timepoint of optimal perinatal outcome.
We present a case of delayed intertwin delivery after delivery of the first twin due to premature prelabor rupture of the membranes. Maternal serum White Blood Cells and C-Reactive Protein levels remained high until delivery of the second twin (34 days after the first was delivered), although maternal temperature remained constant. The mother underwent close antenatal surveillance and she was hospitalized. She had an uncomplicated delivery of the second twin at 29 weeks by cesarean section due to an abnormal Non-Stress Test.
We strongly suggest future evaluation of maternal serum inflammatory markers among these rare cases as these could predict intraamniotic infection.
随着强效和靶向的保胎药物的使用以及产前监测方法变得更加复杂和具体，能够预测最佳围产结局的关键分娩时间点，预计未来几年延迟的双胎分娩间隔时间将会增加。
我们报告了一例因胎膜早破导致第一胎早产分娩后延迟的双胎分娩病例。尽管母体温度保持不变，但母体血清白细胞和 C 反应蛋白水平在第二胎分娩（第一胎分娩后 34 天）前一直很高。母亲接受了密切的产前监测，并因异常无应激试验而住院。她在 29 周时通过剖宫产顺利分娩了第二胎。
我们强烈建议对这些罕见病例中的母体血清炎症标志物进行进一步评估，因为这些标志物可能预测羊膜内感染。
