Chhatre Sumedha, Newman Diane K, Wein Alan J, Jefferson Ashlie E, Schwartz J Sanford, Jayadevappa Ravishankar
Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, 3535 Market St., Suite 4051, Philadelphia, PA, 19104, USA.
Division of Urology, Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
BMC Urol. 2018 Jun 5;18(1):56. doi: 10.1186/s12894-018-0371-2.
Overactive bladder (OAB) affects millions of women. It is important to assess knowledge and attitude in affected patients. The study objective was to develop surveys to assess OAB knowledge and OAB related attitude, and its association with OAB treatment status.
Systematic literature review and qualitative analysis of patient and provider focus groups helped identify OAB knowledge and attitude survey items. We determined psychometric properties of the two surveys in a cross-sectional sample of 104 women, 27% of whom had received OAB treatment.
The OAB-knowledge survey consisted of 16 items and 3 condition-related concepts: perception of OAB; cause and information; and signs of OAB. The OAB-attitude survey consisted of 16 items and its concepts were treatment seeking; decision-making and effects. Both surveys demonstrated good construct validity and test-retest reliability ((≥ 0.60). In the cross-sectional validation sample, OAB-knowledge and attitude discriminated between those with different levels of ICIQ-UI scores. We observed some difference in the OAB knowledge, OAB attitude, and severity of symptoms between those treated for OAB vs. treatment naive.
OAB knowledge and attitude surveys provide a novel tool to assess OAB domains in women. Though we did not find statistical significance in OAB knowledge and attitude scores across treatment status, they may be potentially modifiable factors that affect OAB treatment uptake and treatment compliance. Refinement of these surveys in diverse sub-populations is necessary. Our study provides effect sizes for OAB knowledge and attitude. These effect sizes can help development of fully powered trials to study the association between OAB knowledge and attitude, type and length of treatment, treatment compliance, and quality of life, leading to interventions for enhancing OAB care.
膀胱过度活动症（OAB）影响着数百万女性。评估受影响患者的知识和态度很重要。本研究的目的是开发调查问卷，以评估OAB知识、与OAB相关的态度及其与OAB治疗状态的关联。
通过系统的文献综述以及对患者和医疗服务提供者焦点小组的定性分析，有助于确定OAB知识和态度调查问卷的项目。我们在104名女性的横断面样本中确定了这两项调查问卷的心理测量特性，其中27%的女性接受过OAB治疗。
OAB知识调查问卷包括16个项目和3个与疾病状况相关的概念：对OAB的认知；病因与信息；以及OAB的症状。OAB态度调查问卷包括16个项目，其概念包括寻求治疗；决策制定和影响。两项调查问卷均显示出良好的结构效度和重测信度（≥0.60）。在横断面验证样本中，OAB知识和态度能够区分不同ICIQ-UI评分水平的女性。我们观察到接受过OAB治疗的女性与未接受过治疗的女性在OAB知识、OAB态度和症状严重程度方面存在一些差异。
OAB知识和态度调查问卷为评估女性的OAB领域提供了一种新工具。尽管我们没有发现不同治疗状态下OAB知识和态度得分的统计学显著性差异，但它们可能是影响OAB治疗接受度和治疗依从性的潜在可改变因素。有必要在不同亚人群中对这些调查问卷进行完善。我们的研究提供了OAB知识和态度的效应量。这些效应量有助于开展充分有力的试验，以研究OAB知识和态度、治疗类型和时长、治疗依从性以及生活质量之间的关联，从而制定增强OAB护理的干预措施。
