Suppli Camilla Hiul, Dreier Julie Werenberg, Rasmussen Mette, Andersen Anne-Marie Nybo, Valentiner-Branth Palle, Mølbak Kåre, Krause Tyra Grove
Department of Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen, Denmark.
Department of Public Health, University of Copenhagen, Denmark.
Prev Med Rep. 2018 Feb 23;10:93-99. doi: 10.1016/j.pmedr.2018.02.005. eCollection 2018 Jun.
We aimed to identify sociodemographic predictors of compliance after receiving a personalised reminder on lacking vaccinations against MMR (Measles, Mumps, Rubella) and/or HPV (Human Papilloma Virus) among parents of Danish adolescent girls. A nationwide register-based study, including all 14-year-old girls (15 May 2014-14 May 2015) lacking either MMR, HPV-vaccination or both. Vaccination-compliance following a postal reminder was modelled using multivariable logistic regression and included the following socio-demographic predictors: maternal age, education, employment and ethnicity. Birth order, number of siblings, family-structure, location of residence, and household income. The parents of 9692 girls received a reminder. Out of 4940 exclusively lacking an HPV-vaccine, 15.3% were subsequently vaccinated. Among 2026 only lacking an MMR vaccination, 8.5% were vaccinated. Among 2726 girls lacking both, 5% received an HPV, 4.4% an MMR and 5.4% received both vaccinations. We identified sociodemographic differences between reminderletter-compliers and non-compliers, also according to vaccination types. Non-western descendants were more likely to receive HPV-vaccination, although the association was only significant for those who only lacked HPV (OR 2.02, 95% 1.57-2.59). For girls only lacking an MMR, regional differences were identified. Among girls lacking both vaccines, girls of mothers with intermediate (OR 0.63, 0.42-0.95) or basic education (OR 0.43, 0.24-0.75) were less likely to be vaccinated compared to girls of higher educated mothers. Reminders were in particular effective in increasing HPV uptake among immigrants of non-Western ethnicity. We found reminders to be less effective among less educated mothers whose daughters lacked both vaccines. To increase the coverage in this group, additional interventions are needed.
我们旨在确定丹麦青春期女孩的父母在收到关于缺乏麻疹、腮腺炎、风疹(MMR)和/或人乳头瘤病毒(HPV)疫苗接种的个性化提醒后,依从性的社会人口统计学预测因素。一项基于全国登记册的研究,纳入了所有在2014年5月15日至2015年5月14日期间满14岁且缺乏MMR疫苗接种、HPV疫苗接种或两者均缺乏的女孩。通过多变量逻辑回归对邮寄提醒后的疫苗接种依从性进行建模,纳入以下社会人口统计学预测因素:母亲年龄、教育程度、就业情况和种族。出生顺序、兄弟姐妹数量、家庭结构、居住地点和家庭收入。9692名女孩的父母收到了提醒。在仅缺乏HPV疫苗的4940名女孩中,15.3%随后接种了疫苗。在仅缺乏MMR疫苗的2026名女孩中,8.5%接种了疫苗。在2726名两种疫苗都缺乏的女孩中,5%接种了HPV疫苗,4.4%接种了MMR疫苗,5.4%接种了两种疫苗。我们还根据疫苗接种类型确定了提醒信依从者和不依从者之间的社会人口统计学差异。非西方后裔更有可能接种HPV疫苗,尽管这种关联仅在那些仅缺乏HPV疫苗的人群中显著(比值比2.02,95%可信区间1.57 - 2.59)。对于仅缺乏MMR疫苗的女孩,发现了地区差异。在两种疫苗都缺乏的女孩中,与母亲受高等教育的女孩相比,母亲受中等教育(比值比0.63,0.42 - 0.95)或基础教育(比值比0.43,0.24 - 0.75)的女孩接种疫苗的可能性较小。提醒在提高非西方种族移民的HPV疫苗接种率方面特别有效。我们发现提醒对女儿两种疫苗都缺乏的受教育程度较低的母亲效果较差。为了提高该群体的疫苗接种覆盖率,需要额外的干预措施。