碲霉菌纳米颗粒的合成与研究

Synthesis and investigations on tellurium myconanoparticles.

作者信息

Abo Elsoud Mostafa M, Al-Hagar Ola E A, Abdelkhalek Eman S, Sidkey N M

机构信息

Microbial Biotechnology Dept., National Research Centre (NRC), Giza, Egypt.

Plant Research Dept., Nuclear Research Center, Atomic Energy Authority, Inshas, Egypt.

出版信息

Biotechnol Rep (Amst). 2018 Mar 15;18:e00247. doi: 10.1016/j.btre.2018.e00247. eCollection 2018 Jun.

Tellurium has attracted the attention of many researchers and manufacturers due to its unique properties. Through the current work, six fungal isolates have been screened for their ability to reduce potassium tellurite (KTeO) into elemental tellurium nanoparticles (TeNPs). The most promising fungal isolate was identified as and given the accession number (KY766958) based on molecular basis and has been used for biogenic (enzymatic) production of TeNPs. The produced TeNPs have been characterized using DLS, TEM and FTIR. Data showed that, the particle size is 60.80 d.nm with oval to spherical shape. The produced TeNPs have been evaluated for antimicrobial activity at 25 mg/ml. Data revealed antibacterial activity against and (MRSA). Evaluation of the effect of γ-irradiation on TeNPs production showed that, the productivity was improved at 1 kGy and suppressed gradually at higher doses.

碲因其独特的性质而吸引了众多研究人员和制造商的关注。通过当前的工作，筛选了六种真菌分离株，以评估它们将亚碲酸钾（KTeO）还原为元素碲纳米颗粒（TeNPs）的能力。最有前景的真菌分离株经分子鉴定后被命名为，登录号为（KY766958），并已用于TeNPs的生物合成（酶促）生产。所制备的TeNPs已通过动态光散射（DLS）、透射电子显微镜（TEM）和傅里叶变换红外光谱（FTIR）进行了表征。数据显示，颗粒尺寸为60.80 d.nm，形状为椭圆形至球形。所制备的TeNPs在25mg/ml的浓度下进行了抗菌活性评估。数据显示其对和（耐甲氧西林金黄色葡萄球菌，MRSA）具有抗菌活性。对γ射线辐照对TeNPs生产的影响评估表明，在1kGy时生产率提高，而在较高剂量下逐渐受到抑制。