Payment P, Tremblay M, Trudel M
Appl Environ Microbiol. 1985 Apr;49(4):981-3. doi: 10.1128/aem.49.4.981-983.1985.
Several poliovirus and coxsackievirus isolates from environmental sources were compared with laboratory strains to determine their rate of inactivation by chlorine. All viruses were tested for up to 1,000 min in the presence of an initial free residual chlorine level of ca. 0.4 mg/liter. Coxsackievirus B5 (CB-5) isolates were found to be more resistant to chlorine than coxsackievirus B4 (CB-4), followed by poliovirus 1, 2, and 3 in order of decreasing resistance to chlorine. Environmental isolates of CB-5 were more resistant than the laboratory strain tested, and for two strains 12 and 22% of the input virus was still infectious after 100 min in the presence of free residual chlorine. Although CB-4 isolates were less resistant to chlorine than CB-5 isolates, after 1,000 min of contact 0.01% of the input virus was still infectious. Except for CB-5 isolates, isolates from environmental sources did not appear to be more resistant to chlorine than laboratory strains. Viruses isolated at different phases during the preparation of drinking water were not more resistant to chlorine and must thus have been protected by other mechanisms.
将从环境来源分离出的几种脊髓灰质炎病毒和柯萨奇病毒与实验室菌株进行比较，以确定它们对氯的灭活率。所有病毒在初始游离余氯水平约为0.4毫克/升的情况下进行了长达1000分钟的测试。发现柯萨奇病毒B5（CB - 5）分离株比柯萨奇病毒B4（CB - 4）对氯更具抗性，其次是脊髓灰质炎病毒1、2和3，对氯的抗性依次降低。CB - 5的环境分离株比测试的实验室菌株更具抗性，对于两株菌株，在游离余氯存在100分钟后，仍有12%和22%的输入病毒具有传染性。虽然CB - 4分离株对氯的抗性低于CB - 5分离株，但接触1000分钟后，仍有0.01%的输入病毒具有传染性。除了CB - 5分离株外，环境来源的分离株对氯的抗性似乎并不比实验室菌株更强。在饮用水制备的不同阶段分离出的病毒对氯的抗性并不更强，因此它们一定是通过其他机制受到保护的。
