Harakeh M, Butler M
J Hyg (Lond). 1984 Aug;93(1):157-63. doi: 10.1017/s0022172400061040.
A preparation of infectious human rotavirus, isolated from faeces and resuspended in wastewater effluent, was shown to be inactivated by chlorine, chlorine dioxide, ozone and peracetic acid. Infectivity was assayed in MA 104 cells by the detection of cell-associated viral antigen by immunofluorescence. The inactivation curves were similar to those reported for other enteric viruses. Human rotavirus was at least as resistant as poliovirus, coxsackievirus, echovirus and f2 coliphage and was strikingly less sensitive to inactivation than the simian rotavirus, SA11. The latter was generally the most sensitive of the six tested viruses yet is often taken as being representative of the human rotaviruses.
从粪便中分离出来并重新悬浮于废水流出物中的传染性人轮状病毒制剂，经证明可被氯、二氧化氯、臭氧和过氧乙酸灭活。通过免疫荧光检测细胞相关病毒抗原来测定MA 104细胞中的感染性。灭活曲线与其他肠道病毒的报道曲线相似。人轮状病毒至少与脊髓灰质炎病毒、柯萨奇病毒、埃可病毒和f2噬菌体一样具有抗性，并且对灭活的敏感性明显低于猿猴轮状病毒SA11。后者通常是六种测试病毒中最敏感的，但常被视为人类轮状病毒的代表。
