Gutiérrez-Corrales Aida, Campano-Cuevas Elena, Castillo-Dalí Gabriel, Torres-Lagares Daniel, Gutiérrez-Pérez José-Luis
Stomatology Department. Faculty of Dentistry. Seville, Spain.
J Clin Exp Dent. 2017 May 1;9(5):e716-e722. doi: 10.4317/jced.53776. eCollection 2017 May.
Nowadays, there is a growing interest in using saliva as an alternative sample for the diagnosis, prediction and progression of several diseases. It has been established that some molecules found in saliva are related to oral inflammatory processes and systemic health status. Furthermore, it is known that saliva is crucial for the carrying out of different functions in the oral cavity and its role in the local modulation of inflammatory and immune response is being thoroughly studied by the health research community. The aim of this review is to analyze the most important biomarkers which have been utilized in biomedicine during the last two decades in order to establish a correlation between certain specific salivary biomarkers and systemic inflammation. Then, we discuss the utility of total proteins, immunoglobulin A and alpha-amylase as biomarkers for the prognostic of local inflammation after oral surgery. Inflammation, salivary biomarkers, systemic disease, buccal surgery, total proteins, inmunoglobulin A, Alpha-amylase.
如今，人们越来越关注将唾液作为多种疾病诊断、预测和病情进展的替代样本。已经证实，唾液中发现的一些分子与口腔炎症过程和全身健康状况有关。此外，众所周知，唾液对于口腔中不同功能的执行至关重要，健康研究界正在深入研究其在局部调节炎症和免疫反应中的作用。本综述的目的是分析过去二十年在生物医学中使用的最重要的生物标志物，以便在某些特定的唾液生物标志物与全身炎症之间建立关联。然后，我们讨论总蛋白、免疫球蛋白A和α-淀粉酶作为口腔手术后局部炎症预后生物标志物的效用。炎症、唾液生物标志物、全身性疾病、口腔手术、总蛋白、免疫球蛋白A、α-淀粉酶。
