Amra Babak, Rahmati Behzad, Soltaninejad Forogh, Feizi Awat
Bamdad Respiratory and Sleep Research Center, Pulmonary Ward, Department of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Department of Internal Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Oman Med J. 2018 May;33(3):184-192. doi: 10.5001/omj.2018.36.
Obstructive sleep apnea (OSA) is the most common sleep-related breathing disorder and is associated with significant morbidity. We sought to present an updated systematic review of the literature on the accuracy of screening questionnaires for OSA against polysomnography (PSG) as the reference test. Using the main databases (including Medline, Cochrane Database of Systematic Reviews and Scopus) we used a combination of relevant keywords to filter studies published between January 2010 and April 2017. Population-based studies evaluating the accuracy of screening questionnaires for OSA against PSG were included in the review. Thirty-nine studies comprising 18 068 subjects were included. Four screening questionnaires for OSA had been validated in selected studies including the Berlin questionnaire (BQ), STOP-Bang Questionnaire (SBQ), STOP Questionnaire (SQ), and Epworth Sleepiness Scale (ESS). The sensitivity of SBQ in detecting mild (apnea-hypopnea index (AHI) ≥ 5 events/hour) and severe (AHI ≥ 30 events/hour) OSA was higher compared to other screening questionnaires (range from 81.08% to 97.55% and 69.2% to 98.7%, respectively). However, SQ had the highest sensitivity in predicting moderate OSA (AHI ≥ 15 events/hour; range = 41.3% to 100%). SQ and SBQ are reliable tools for screening OSA among sleep clinic patients. Although further validation studies on the screening abilities of these questionnaires on general populations are required.
阻塞性睡眠呼吸暂停（OSA）是最常见的与睡眠相关的呼吸障碍，且与严重的发病率相关。我们试图对以多导睡眠图（PSG）作为参考测试的OSA筛查问卷准确性的文献进行更新的系统评价。利用主要数据库（包括医学文献数据库、Cochrane系统评价数据库和Scopus），我们使用相关关键词组合筛选2010年1月至2017年4月发表的研究。纳入以人群为基础、评估OSA筛查问卷相对于PSG准确性的研究。纳入了39项研究，共18068名受试者。在选定的研究中已验证了4种OSA筛查问卷，包括柏林问卷（BQ）、STOP-Bang问卷（SBQ）、STOP问卷（SQ）和爱泼华嗜睡量表（ESS）。与其他筛查问卷相比，SBQ在检测轻度（呼吸暂停低通气指数（AHI）≥5次/小时）和重度（AHI≥30次/小时）OSA方面的敏感性更高（分别为81.08%至97.55%和69.2%至98.7%）。然而，SQ在预测中度OSA（AHI≥15次/小时；范围为41.3%至100%）方面具有最高的敏感性。SQ和SBQ是睡眠诊所患者中筛查OSA的可靠工具。尽管需要对这些问卷在一般人群中的筛查能力进行进一步的验证研究。
