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关于一种制备含有高氧分压和低二氧化碳分压溶液的简单方法的数据。

Data on a simple method for producing a solution that contains a high partial pressure of oxygen and a low partial pressure of carbon dioxide.

作者信息

Tange Yoshihiro, Yoshitake Shigenori

机构信息

Department of Medical Engineering, Kyushu University of Health and Welfare, Japan.

出版信息

Data Brief. 2018 Mar 8;18:176-179. doi: 10.1016/j.dib.2018.02.079. eCollection 2018 Jun.

DOI:10.1016/j.dib.2018.02.079
PMID:29896508
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5996131/
Abstract

The data presented here shows a simple method for producing a solution that contains a high partial pressure of oxygen (pO) and a low partial pressure of carbon dioxide (pCO). This novel solution was created by simply injecting oxygen gas into conventional supplemental bicarbonate fluid for renal replacement therapy. We compared the gas profiles of the novel solution and the conventional fluid in vitro. There was a significant increase in pO and pH, and a significant decrease in pCO in the experimental solution, in each of which an additional volume of oxygen was injected. The method shown here is capable of facilitating an increase of pO and decrease of pCO by using a closed fluid bag without any special devices.

摘要

此处呈现的数据展示了一种制备含有高氧分压(pO)和低二氧化碳分压(pCO)溶液的简单方法。这种新型溶液是通过将氧气简单注入用于肾脏替代治疗的传统补充碳酸氢盐溶液中而制成的。我们在体外比较了新型溶液和传统溶液的气体成分。在每种注入额外体积氧气的实验溶液中,pO和pH显著升高,pCO显著降低。此处所示方法能够通过使用封闭的液体袋且无需任何特殊装置来促进pO升高和pCO降低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4e8/5996131/8566b90cc578/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4e8/5996131/e17724e76649/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4e8/5996131/accd69747d05/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4e8/5996131/8566b90cc578/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4e8/5996131/e17724e76649/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4e8/5996131/accd69747d05/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4e8/5996131/8566b90cc578/gr3.jpg

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本文引用的文献

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Intravenous administration of hyperoxygenated solution attenuates pulmonary edema formation in phosgene-induced acute lung injury in rabbits.静脉给予高氧溶液可减轻光气致兔急性肺损伤肺水肿的形成。
J Surg Res. 2010 Nov;164(1):131-8. doi: 10.1016/j.jss.2008.09.017. Epub 2008 Oct 14.
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The effects of intravenous hyperoxygenated solution infusion on systemic oxygenation and intrapulmonary shunt during one-lung ventilation in pigs.
静脉内高氧溶液输注对猪单肺通气期间全身氧合和肺内分流的影响。
J Surg Res. 2010 Apr;159(2):653-9. doi: 10.1016/j.jss.2008.09.014. Epub 2008 Oct 14.
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Hyperoxygenated solution preconditioning attenuates lung injury induced by intestinal ischemia reperfusion in rabbits.高氧溶液预处理减轻兔肠缺血再灌注诱导的肺损伤。
J Surg Res. 2008 May 1;146(1):24-31. doi: 10.1016/j.jss.2007.07.008. Epub 2007 Aug 21.