Zuccaro Jennifer, Muser Inga, Singh Manni, Yu Janelle, Kelly Charis, Fish Joel
Department of Plastic and Reconstructive Surgery, Hospital for Sick Children, Toronto, Ontario, Canada.
Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada.
J Burn Care Res. 2018 Apr 20;39(3):457-462. doi: 10.1093/jbcr/irx008.
Treatment with laser therapy has the potential to greatly improve hypertrophic scarring in individuals who have sustained burn injuries. More specifically, recent research has demonstrated the success of using pulsed dye laser therapy to help reduce redness and postburn pruritus and using ablative fractional CO2 laser therapy to improve scar texture and thickness. This study describes our early experience using laser therapy in our pediatric burn program and details our specific treatment approach when using each laser individually and in combination during the same procedure. A retrospective before-after study of patients with hypertrophic burn scars who were treated with laser therapy at our pediatric institution was performed. One hundred and twenty-five patients were treated over a total of 289 laser sessions with more than 50% of patients under the age of 5 years at the first treatment. The majority of procedures were performed using both the pulsed dye and CO2 lasers in combination. Before-after Vancouver Scar Scale scores decreased from 7.37 (SD, 2.46) to 5.76 (SD, 2.29) after a single treatment. The results obtained from this study support the use of laser therapy to improve hypertrophic burn scars in the pediatric population. Rigorous randomized controlled trials are needed to confirm the effectiveness of this therapy.
激光治疗有潜力极大地改善烧伤患者的增生性瘢痕。更具体地说，最近的研究表明，使用脉冲染料激光治疗有助于减轻发红和烧伤后瘙痒，使用剥脱性分数二氧化碳激光治疗可改善瘢痕质地和厚度。本研究描述了我们在儿科烧伤项目中使用激光治疗的早期经验，并详细介绍了在同一过程中单独使用每种激光以及联合使用时的具体治疗方法。我们对在我们儿科机构接受激光治疗的增生性烧伤瘢痕患者进行了一项回顾性前后对照研究。共有125名患者接受了289次激光治疗，超过50%的患者首次治疗时年龄在5岁以下。大多数治疗程序同时使用了脉冲染料激光和二氧化碳激光。单次治疗后，温哥华瘢痕量表前后评分从7.37（标准差，2.46）降至5.76（标准差，2.29）。本研究获得的结果支持使用激光治疗改善儿科患者的增生性烧伤瘢痕。需要进行严格的随机对照试验来证实这种治疗方法的有效性。
