Murphy G P, Tritsch G L, Sufrin G, Williams P D
Urology. 1985 Jun;25(6):622-4. doi: 10.1016/0090-4295(85)90295-x.
In the Wistar/Furth rat, twenty-four hours after unilateral nephrectomy, the remaining contralateral kidney produces maximum amounts of renotropic growth factors. These factors stimulate tumor growth in recipient rats with s.c. Wilms tumor, but have no effect on kidney weight. In tumor-free recipients, kidney hypotrophy results when the factors are administered.
在Wistar/Furth大鼠中,单侧肾切除术后24小时,剩余的对侧肾脏会产生最大量的促肾生长因子。这些因子会刺激皮下接种威尔姆斯瘤的受体大鼠的肿瘤生长,但对肾脏重量没有影响。在无肿瘤的受体中,给予这些因子会导致肾脏萎缩。