Al-Husseini Amneh, Wazaify Mayyada, Van Hout Marie Claire
1Department of Biopharmaceutics and Clinical Pharmacy, School of Pharmacy, The University of Jordan (UJ), Amman, Jordan.
Public Health Institute, Liverpool John Moore's University, Liverpool, UK.
Int J Ment Health Addict. 2018;16(3):642-654. doi: 10.1007/s11469-017-9813-4. Epub 2017 Sep 15.
Pregabalin is currently approved for the treatment of epilepsy, generalized anxiety disorder, neuropathic pain, and fibromyalgia. A qualitative study was undertaken in Jordan, where concerns have been raised about its unprescribed availability in community pharmacies and thereby its abuse. Semi-structured interviews were conducted with all patients with a history of pregabalin use in two Jordanian addiction treatment centers. All were male patients aged 21-30 years ( = 11). The majority was poly-drug abusers and had a previous history of substance abuse (tramadol, Captagon, synthetic cannabinoids, and marijuana) Six key themes emerged from a content textual analysis which centered on ; ; ; , , ; ; and . The study underscores the need for continued pharmacovigilance to manage and address suspected abuse, along with community pharmacist and patient education regarding abuse liability and related harms.
普瑞巴林目前被批准用于治疗癫痫、广泛性焦虑障碍、神经性疼痛和纤维肌痛。在约旦进行了一项定性研究，该国对社区药房中普瑞巴林的非处方可得性及其滥用情况表示担忧。对约旦两个成瘾治疗中心所有有普瑞巴林使用史的患者进行了半结构化访谈。所有患者均为21至30岁的男性（n = 11）。大多数人是多药滥用者，并有药物滥用史（曲马多、卡西酮、合成大麻素和大麻）。内容文本分析中出现了六个关键主题，集中在；；；，，；；和。该研究强调需要持续开展药物警戒以管理和应对疑似滥用情况，同时对社区药剂师和患者进行关于滥用风险及相关危害的教育。
