Ferioli Martina, Zauli Giorgio, Martelli Alberto M, Vitale Marco, McCubrey James A, Ultimo Simona, Capitani Silvano, Neri Luca M
Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy.
Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy.
Oncotarget. 2018 Feb 8;9(17):14005-14034. doi: 10.18632/oncotarget.24456. eCollection 2018 Mar 2.
Cancer patients experience symptoms and adverse effects of treatments that may last even after the end of treatments. Exercise is a safe, non-pharmacological and cost-effective therapy that can provide several health benefits in cancer patient and survivors, reducing cancer symptoms and cancer treatment side effects. The purpose of this review is to describe how the physical exercise is capable to reduce cancer symptoms and cancer treatment side effects. We realized a pragmatic classification of symptoms, dividing them into physical, psychological and psycho-physical aspects. For each symptom we discuss causes, therapies, we analyse the effects of physical exercise and we summarize the most effective type of exercise to reduce the symptoms. This review also points out what are the difficulties that patients and survivors face during the practice of physical activity and provides some solutions to overcome these barriers. Related to each specific cancer, it emerges that type, frequency and intensity of physical exercise could be prescribed and supervised as a therapeutic program, like it occurs for the type, dose and duration of a drug treatment.
癌症患者会经历治疗带来的症状和不良反应,这些症状甚至可能在治疗结束后仍持续存在。运动是一种安全、非药物且具有成本效益的疗法,可为癌症患者及其幸存者带来诸多健康益处,减轻癌症症状和癌症治疗的副作用。本综述的目的是描述体育锻炼如何能够减轻癌症症状和癌症治疗的副作用。我们对症状进行了务实的分类,将其分为身体、心理和身心方面。对于每种症状,我们讨论其成因、治疗方法,分析体育锻炼的效果,并总结减轻症状最有效的运动类型。本综述还指出了患者及其幸存者在进行体育活动时面临的困难,并提供了一些克服这些障碍的解决方案。与每种特定癌症相关的是,体育锻炼的类型、频率和强度可以像药物治疗的类型、剂量和持续时间一样,作为一种治疗方案进行规定和监督。