立体选择性反应。VIII. 木脂素内酯苄基氧化的立体化学要求。通过氧化斯替甘进行抗肿瘤木脂素内酯斯替加南的高选择性合成。 - Suppr

Suppr

超能文献

Stereoselective reactions. VIII. Stereochemical requirement for the benzylic oxidation of lignan lactone. A highly selective synthesis of the antitumor lignan lactone steganacin by the oxidation of stegane.

作者信息

Ishiguro T, Mizuguchi H, Tomioka K, Koga K

出版信息

Chem Pharm Bull (Tokyo). 1985 Feb;33(2):609-17. doi: 10.1248/cpb.33.609.

DOI:10.1248/cpb.33.609

PMID:2990746

Abstract

摘要

相似文献

Stereoselective reactions. VIII. Stereochemical requirement for the benzylic oxidation of lignan lactone. A highly selective synthesis of the antitumor lignan lactone steganacin by the oxidation of stegane.立体选择性反应。VIII. 木脂素内酯苄基氧化的立体化学要求。通过氧化斯替甘进行抗肿瘤木脂素内酯斯替加南的高选择性合成。

Chem Pharm Bull (Tokyo). 1985 Feb;33(2):609-17. doi: 10.1248/cpb.33.609.

Stereoselective reactions. XII. Synthesis of antitumor-active steganacin analogs, picrosteganol and epipicrosteganol, by selective isomerization.

Chem Pharm Bull (Tokyo). 1986 Apr;34(4):1501-4. doi: 10.1248/cpb.34.1501.

Absolute structure-cytotoxic activity relationships of steganacin congeners and analogues.隐丹参酮同系物和类似物的绝对结构-细胞毒性活性关系

J Med Chem. 1991 Jan;34(1):54-7. doi: 10.1021/jm00105a009.

[Asymmetric total synthesis of some biologically active natural products].[某些生物活性天然产物的不对称全合成]

Yakugaku Zasshi. 1984 Oct;104(10):1009-23. doi: 10.1248/yakushi1947.104.10_1009.

Improved stereoselective synthesis of optically active methylene lactone, key intermediate for the synthesis of 1,2-oxidized furofuran lignan, by direct alpha-methylenation to butanolide.通过直接α-亚甲基化反应生成丁内酯，实现了光学活性亚甲基内酯的立体选择性合成改进，亚甲基内酯是合成1,2-氧化呋喃并呋喃木脂素的关键中间体。

Biosci Biotechnol Biochem. 2000 Oct;64(10):2209-15. doi: 10.1271/bbb.64.2209.

alpha,beta-Dibenzyl-gamma-butyrolactone lignan alcohols: total synthesis of (+/-)-7'-hydroxyenterolactone, (+/-)-7'-hydroxymatairesinol and (+/-)-8-hydroxyenterolactone.

Steroids. 2001 Oct;66(10):777-84. doi: 10.1016/s0039-128x(01)00107-6.

Diversity oriented microwave-assisted synthesis of (-)-steganacin aza-analogues.面向多样性的微波辅助合成（-）-斯替加那辛氮杂类似物

J Org Chem. 2008 Oct 3;73(19):7509-16. doi: 10.1021/jo801290j. Epub 2008 Aug 28.

Stereoselectivity questions in the synthesis of wikstromol.维克斯托莫合成中的立体选择性问题。

J Nat Prod. 1990 Nov-Dec;53(6):1587-92. doi: 10.1021/np50072a034.

Total synthesis and structure confirmation of the annonaceous acetogenins 30(S)-hydroxybullatacin, uvarigrandin a, and 5(R)-uvarigrandin a (narumicin I?).番荔枝科乙酰精宁类化合物30(S)-羟基布拉他辛、乌瓦立苷A和5(R)-乌瓦立苷A（那鲁米星I？）的全合成及结构确证

J Org Chem. 2003 Mar 7;68(5):1780-5. doi: 10.1021/jo0266137.

In vitro antitumor activities of new synthetic bistetrahydrofuran derivatives as analogs of Annonaceous acetogenins.新型合成双四氢呋喃衍生物作为番荔枝科杀鱼菌素类似物的体外抗肿瘤活性

Chem Pharm Bull (Tokyo). 1998 Jan;46(1):154-8. doi: 10.1248/cpb.46.154.

引用本文的文献

Levoglucosenone as a starting material for cascade continuous-flow synthesis of (R)-γ-carboxy-γ-butyrolactone.左旋葡聚糖酮作为用于（R）-γ-羧基-γ-丁内酯级联连续流合成的起始原料。

RSC Adv. 2024 Oct 29;14(47):34611-34619. doi: 10.1039/d4ra06403h.

Screening of Promising Chemotherapeutic Candidates from Plants against Human Adult T-Cell Leukemia/Lymphoma (VII): Active Principles from L.筛选具有潜力的植物化疗候选药物以对抗人类成人 T 细胞白血病/淋巴瘤（VII）：来自 L. 的活性成分

Molecules. 2021 Dec 15;26(24):7619. doi: 10.3390/molecules26247619.

Secondary Metabolites with Antimycobacterial Activities from One Actinobacteria: .一株放线菌来源的具有抗分枝杆菌活性的次生代谢产物:.

Molecules. 2021 Oct 15;26(20):6236. doi: 10.3390/molecules26206236.

Recent strategies and tactics for the enantioselective total syntheses of cyclolignan natural products.近期手性全合成环木脂素天然产物的策略和战术。

Nat Prod Rep. 2022 Mar 23;39(3):670-702. doi: 10.1039/d1np00057h.

Oxidative Transformations of Lignans.木质素的氧化转化。

Molecules. 2019 Jan 15;24(2):300. doi: 10.3390/molecules24020300.

Enantioselective α-Alkylation of Aldehydes by Photoredox Organocatalysis: Rapid Access to Pharmacophore Fragments from β-Cyanoaldehydes.光氧化还原有机催化实现醛的对映选择性α-烷基化：从β-氰基醛快速获取药效团片段

Angew Chem Int Ed Engl. 2015 Aug 10;54(33):9668-72. doi: 10.1002/anie.201503789. Epub 2015 Jun 30.

Synthesis of 3,4-dibenzyltetrahydrofuran lignans (9,9'-epoxylignanes).合成 3,4-二苄基四氢呋喃木脂素（9,9'-氧化木脂素）。

Molecules. 2013 Oct 24;18(11):13124-38. doi: 10.3390/molecules181113124.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验