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撤回:外源性硫化氢通过抑制慢性阻塞性肺疾病大鼠模型内质网应激对肺动脉内皮细胞的保护作用。

RETRACTED: Protective effect of exogenous hydrogen sulfide on pulmonary artery endothelial cells by suppressing endoplasmic reticulum stress in a rat model of chronic obstructive pulmonary disease.

机构信息

Division of Respiratory and Critical Care Medicine, First Affiliated Hospital of Fujian Medical University, Fuzhou, 350005, Fujian Province, PR China.

Division of Respiratory and Critical Care Medicine, First Affiliated Hospital of Fujian Medical University, Fuzhou, 350005, Fujian Province, PR China.

出版信息

Biomed Pharmacother. 2018 Sep;105:734-741. doi: 10.1016/j.biopha.2018.05.131. Epub 2018 Jun 14.

DOI:10.1016/j.biopha.2018.05.131
PMID:29908494
Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the Editor-in-Chief. An Expression of Concern for this article was previously published while an investigation was conducted (see related editorial: https://doi.org/10.1016/j.biopha.2022.113812). This retraction notice supersedes the Expression of Concern published earlier. Concern was raised about the reliability of the Western blot data in Figure 4A, which appear to represent a distinct phenotype as found in many other publications, as detailed here: https://pubpeer.com/publications/029A84E50BD071A2088140723E3CF0; and here: https://docs.google.com/spreadsheets/d/1r0MyIYpagBc58BRF9c3luWNlCX8VUvUuPyYYXzxWvgY/edit#gid=262337249. Independent analysis confirmed the presence of suspected image duplications between the Western blots in Figure 4A and those contained in Yan et al (2017). The journal requested the corresponding author comment on these concerns and provide the associated raw data. The authors did not respond to this request and therefore the Editor-in-Chief decided to retract the article.

摘要

本文已被撤回

请参阅 Elsevier 撤稿政策(http://www.elsevier.com/locate/withdrawalpolicy)。应主编要求撤回本文。在进行调查时,曾发表过对此文的关注(参见相关社论:https://doi.org/10.1016/j.biopha.2022.113812)。本撤稿通知取代了先前发表的关注。对图 4A 中的 Western blot 数据的可靠性提出了质疑,这些数据似乎代表了许多其他出版物中发现的明显表型,详细内容如下:https://pubpeer.com/publications/029A84E50BD071A2088140723E3CF0;以及这里:https://docs.google.com/spreadsheets/d/1r0MyIYpagBc58BRF9c3luWNlCX8VUvUuPyYYXzxWvgY/edit#gid=262337249。独立分析证实,图 4A 中的 Western blot 之间存在疑似图像重复,与 Yan 等人(2017 年)包含的 Western blot 之间存在疑似图像重复。期刊要求通讯作者对这些问题发表评论,并提供相关原始数据。作者未对此请求作出回应,因此主编决定撤回该文章。

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