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免疫功能正常患者中假牙相关口腔微生物群与导致厌氧性化脓性肝脓肿的牙周病:一例病例报告及文献综述

Denture-Associated Oral Microbiome and Periodontal Disease Causing an Anaerobic Pyogenic Liver Abscess in an Immunocompetent Patient: A Case report and Review of the Literature.

作者信息

Hammami Muhammad Bader, Noonan Elizabeth M, Chhaparia Anuj, Khatib Feras Al, Bassuner Juri, Hachem Christine

机构信息

Department of Internal Medicine, Division of Gastroenterology and Hepatology, Saint Louis University School of Medicine, St Louis, MO, USA.

Department of Pediatrics, Saint Louis University School of Medicine, Saint Louis, MO, USA.

出版信息

Gastroenterology Res. 2018 Jun;11(3):241-246. doi: 10.14740/gr1006w. Epub 2018 May 31.

DOI:10.14740/gr1006w
PMID:29915637
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5997471/
Abstract

Pyogenic liver abscesses (PLA) develop from the spread of infection through the portal circulation, biliary infections or arterial hematogenous seeding in the setting of systemic infections. PLA are often poly-microbial and are uncommonly reported to be due to anaerobic species. We report the case of a previously healthy, immunocompetent 63-year-old man with hepatic abscesses as a result of periodontal disease. In addition, a systemic review of the literature is performed. is a very rare cause of PLA in immunocompetent hosts with only a handful of cases reported in the literature. Although anaerobic infections such as most often occur in immunocompromised individuals, clinicians should have a high index of suspicion in immunocompetent patients with periodontal disease or chronic stomatitis.

摘要

化脓性肝脓肿(PLA)是由感染通过门静脉循环扩散、胆道感染或全身性感染时的动脉血行播散引起的。PLA通常是多微生物感染,很少有报道称是由厌氧菌引起的。我们报告了一例先前健康、免疫功能正常的63岁男性因牙周病导致肝脓肿的病例。此外,还对文献进行了系统回顾。在免疫功能正常的宿主中,牙周病是PLA非常罕见的病因,文献中仅报道了少数病例。虽然诸如[此处原文缺失具体厌氧菌名称]等厌氧菌感染最常发生在免疫功能低下的个体中,但临床医生对患有牙周病或慢性口腔炎的免疫功能正常患者应保持高度怀疑。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9708/5997471/d38656aa3b49/gr-11-241-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9708/5997471/e0199b87a0bf/gr-11-241-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9708/5997471/c5dceecb67c1/gr-11-241-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9708/5997471/f15ddd05d40e/gr-11-241-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9708/5997471/d38656aa3b49/gr-11-241-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9708/5997471/e0199b87a0bf/gr-11-241-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9708/5997471/c5dceecb67c1/gr-11-241-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9708/5997471/f15ddd05d40e/gr-11-241-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9708/5997471/d38656aa3b49/gr-11-241-g004.jpg

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