Department of Chemistry, University of Cincinnati, Cincinnati, OH, 45221, USA.
Mikrochim Acta. 2018 Jun 18;185(7):330. doi: 10.1007/s00604-018-2870-y.
A surface-enhanced Raman scattering (SERS) method has been developed to determine the concentration of trichloroethylene (TCE) in environmental water. Au-core/Ag-shell nanoparticles containing 4-mercaptophenylboronic acid (4-MPBA) between the core and shell are used as the SERS substrate. 4-MPBA serves as an internal reference with a Raman shift at 534 cm. TCE reacts with 4-mercaptopyridine (4-MPy) in a so-called Fujiwara reaction. With the presence of TCE in water, the consumption of 4-MPy results in a change in the intensity of its Raman signal at 1220 cm. The ratio of the Raman shift at 1220 cm and 534 cm decreases linearly in the 0.2 to 1.0 μM TCE concentration range, and the detection limit of TCE is as low as 8 ppb (60 nM). The method has been successfully applied to the determination of TCE in spiked lake water. Graphical abstract Gold-core/silver-shell nanoparticles with internal reference embedded have been fabracated to improve the quantitative measurement of SERS. These nanoparticles as SERS substrates, are used to indirectly quantify the concentration of trichloroethylene (a typical halogenated organic compound) by the consumption of 4-mercaptopyridine through the Fujiwara reaction.
已开发出一种表面增强拉曼散射（SERS）方法来测定环境水中三氯乙烯（TCE）的浓度。Au 核/Ag 壳纳米粒子在核和壳之间含有 4-巯基苯硼酸（4-MPBA），用作 SERS 基底。4-MPBA 用作内标，拉曼位移为 534cm。TCE 与 4-巯基吡啶（4-MPy）在所谓的藤原反应中发生反应。在水中存在 TCE 的情况下，4-MPy 的消耗会导致其在 1220cm 处的拉曼信号强度发生变化。在 0.2 至 1.0μM TCE 浓度范围内，1220cm 和 534cm 处的拉曼位移之比呈线性下降，TCE 的检测限低至 8ppb（60nM）。该方法已成功应用于测定加标湖水样品中的 TCE。嵌入内标物的金核/银壳纳米粒子已被制备以提高 SERS 的定量测量。这些纳米粒子作为 SERS 基底，通过藤原反应中 4-巯基吡啶的消耗，被用来间接定量测定三氯乙烯（一种典型的卤代有机化合物）的浓度。
