Rock D L, Fraser N W
J Virol. 1985 Sep;55(3):849-52. doi: 10.1128/JVI.55.3.849-852.1985.
Southern blot analysis of latent herpes simplex virus DNA detected in mouse brain and digested with a restriction enzyme revealed two copies of the virion DNA joint fragment. Thus, the absence of free ends noted previously in latent herpes simplex virus type 1 DNA is due to joining of the termini.
对在小鼠脑中检测到并用限制性酶消化的潜伏性单纯疱疹病毒DNA进行Southern印迹分析,结果显示有两个病毒体DNA连接片段拷贝。因此,先前在1型潜伏性单纯疱疹病毒DNA中观察到的无游离末端现象是由于末端的连接所致。