Ulu Murat, Kılıç Erdem, Soylu Emrah, Kürkçü Mehmet, Alkan Alper
Faculty of Dentistry, Oral and Maxillofacial Department, İzmir Katip Celebi University, İzmir, Turkey.
Faculty of Dentistry, Oral and Maxillofacial Department, Bezmialem University, İstanbul, Turkey.
Int J Implant Dent. 2018 Jun 19;4(1):22. doi: 10.1186/s40729-018-0130-x.
The aim of this study was to histomorphometrically compare the implant-host integration between retrieved implants and new implants.
Jaws in 10 male beagle dogs were divided into four groups, and 36 dental implants were inserted into the jaws. In groups 1 and 2, experimental peri-implantitis was induced within 2 months after implant insertion. In group 1, surface decontamination of implants was achieved using air-flow and citric acid. In group 2, implants were sterilized with autoclave after air-flow and citric acid surface decontamination. Subsequently, these implants were inserted in contralateral jaws of the same dogs and a 3-month period was allowed for osseointegration. In group 3, the implants were removed from human jaws due to peri-implantitis and were inserted into dog jaws following surface cleaning protocol and sterilization with autoclave and a 3-month period was allowed for osseointegration. Group 4 was set as the control group. After the osseointegration period, all the animals were sacrificed. The degree of osseointegration in all groups was evaluated by evaluating the ISQ values and by using histomorphometric measurements.
Histological findings showed that bone-implant contact (BIC) percentage (mean ± SD) was 83.39% ± 6.37 in group 1, 79.93% ± 11.83 in group 2, 75.45% ± 9.09 in group 3, and 80.53 ± 5.22 in group 4. Moreover, the resonance frequency analysis (RFA) and ISQ values were similar in all four groups both before and after the implantation.
The results of this experimental study indicated that there is no significant difference between new dental implants and re-used dental implants with regards to osseointegration around the implant.
本研究的目的是通过组织形态计量学比较取出的种植体与新种植体的种植体-宿主整合情况。
将10只雄性比格犬的颌骨分为四组，共植入36颗牙种植体。在第1组和第2组中，在种植体植入后2个月内诱导实验性种植体周围炎。在第1组中，使用气流和柠檬酸对种植体进行表面去污。在第2组中，在气流和柠檬酸表面去污后，用高压灭菌器对种植体进行消毒。随后，将这些种植体植入同一只狗的对侧颌骨，并给予3个月的骨整合期。在第3组中，因种植体周围炎从人类颌骨中取出种植体，按照表面清洁方案进行处理，并用高压灭菌器消毒，然后植入狗颌骨，并给予3个月的骨整合期。第4组作为对照组。骨整合期结束后，处死所有动物。通过评估种植体稳定性商数（ISQ）值和组织形态计量学测量来评估所有组的骨整合程度。
组织学结果显示，第1组的骨-种植体接触（BIC）百分比（平均值±标准差）为83.39%±6.37，第2组为79.93%±11.83，第3组为75.45%±9.09，第4组为80.53±5.22。此外，在植入前后，所有四组的共振频率分析（RFA）和ISQ值均相似。
本实验研究结果表明，新牙种植体和再利用牙种植体在种植体周围骨整合方面没有显著差异。
